What Is Retatrutide? A Research Peptide Overview
Retatrutide is a synthetic peptide that acts as a triple receptor agonist at GLP-1, GIP, and glucagon receptors. It is one of the most studied peptides in metabolic research.
Chemical properties
- Structure: 39-amino-acid peptide with multiple modifications
- Molecular weight: ~4,838.5 g/mol
- CAS Number: 2023788-19-2
- Appearance: White to off-white lyophilized powder
What retatrutide is studied for
In laboratory research:
- Triple agonism — simultaneously activates GLP-1, GIP, and glucagon receptors
- Metabolic signaling — studied for effects on energy expenditure and glucose homeostasis
- Receptor pharmacology — researched for binding affinity profiles across three receptor types
How retatrutide is verified
- HPLC — purity >=99% by peak area
- Mass spectrometry — observed mass matching theoretical mass
- LAL endotoxin — below research-grade thresholds
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FAQ
What is retatrutide peptide?
Retatrutide is a 39-amino-acid synthetic peptide that acts as a triple agonist at GLP-1, GIP, and glucagon receptors, studied in metabolic research.
How is retatrutide different from tirzepatide?
Tirzepatide is a dual agonist (GLP-1 + GIP). Retatrutide adds glucagon receptor agonism, making it a triple agonist.