AICAR 50mg

AICAR (5-Aminoimidazole-4-carboxamide ribonucleotide, also called ZMP) is a cell-permeable nucleotide analog widely used as a pharmacological activator of AMP-activated protein kinase (AMPK) in cell and tissue culture studies.

AMPK is a central cellular energy sensor; AICAR is used experimentally to probe AMPK-dependent signaling cascades, mitochondrial biogenesis markers, and glucose-uptake pathways in skeletal muscle and hepatocyte cell lines.

For in-vitro assay preparation, researchers calculate a target concentration (mg/mL) from the vial's labeled mass and the volume of sterile diluent added, then aliquot and store per standard laboratory cold-chain practice. This is a laboratory dilution calculation only, performed strictly for analytical or in-vitro research purposes. Not for use in humans or animals.

Lyophilized powder should be stored at -20°C for long-term stability, or refrigerated (2-8°C) for short-term use, protected from light and moisture. Once reconstituted for laboratory use, follow standard cold-chain handling and use within the timeframe indicated by your institution's protocols.

AICAR ships with a QR-linked, batch-specific certificate of analysis (COA) confirming identity and purity via HPLC. Researchers should always confirm the lot number on their vial matches the COA on file before beginning any assay.

This reference material is manufactured and quality-tested to support reproducible research outcomes. Every batch is independently verified before it ships, and COAs remain accessible for future reference.