Research use only. Not for use in humans or animals. All products and information on this site are provided strictly for in-vitro laboratory research purposes and are supplied as research chemicals only.
What Is Dihexa? A Research Compound Overview
Dihexa is a peptidomimetic research compound derived from angiotensin IV, studied extensively in neuroscience literature on synapse formation. It is described as acting through the HGF/c-Met system in model systems. This overview covers what dihexa is, what researchers study it for, and how to verify research-grade material.
Dihexa at a glance
| Property | Value |
| --- | --- |
| Name | Dihexa (N-hexanoic-Tyr-Ile-(6) aminohexanoic amide) |
| Class | Angiotensin-IV-derived peptidomimetic |
| Research area | Synaptogenesis, HGF/c-Met signaling (in vitro) |
| Format | Research capsules |
| Purity | ≥98% (HPLC) |
| Intended use | Laboratory research only |
Research background
Dihexa was developed in academic neuroscience research as a metabolically stable analog of angiotensin IV. In model systems it is studied as a modulator of the hepatocyte growth factor (HGF) / c-Met receptor system, which is implicated in synapse-formation research. Its stability and potency in these assays made it a widely referenced tool compound in cognition-model literature.
What Dihexa is studied for
In laboratory research (cell-culture and non-clinical model systems), Dihexa is studied for its role in:
- Synaptogenesis research — dendritic-spine and synapse-formation model systems.
- HGF/c-Met signaling — receptor-pathway characterisation in cultured cells.
- Angiotensin-IV pharmacology — as a stable analog reference compound.
All of this is laboratory research; Dihexa offered here is a research chemical only, supplied for in-vitro and non-clinical study.
How research-grade Dihexa is verified
Every batch that ships from a credible US supplier should arrive with a third-party Certificate of Analysis (COA) for that exact lot. Peptide Technologies publishes a COA on every batch and ties it to a QR code on the vial. A complete COA reports:
- Identity — mass spectrometry (ESI-MS) confirming the observed mass matches the theoretical mass of the target compound.
- Purity — reverse-phase HPLC, reported as percent peak area (typically at 220 nm). Research-grade material is ≥98–99% by area.
- Net content — gravimetric confirmation the vial holds the stated mass within tolerance.
- Endotoxin — LAL assay below research thresholds, where applicable.
If a vendor cannot show you a lot-specific COA, you cannot verify what is in the vial. Browse the public COA library →
How to source research-grade material
For laboratory research, sourcing quality comes down to a few checks:
- Lot-specific COA from an accredited, independent laboratory — not a generic marketing PDF.
- HPLC purity ≥98% by peak area, with the chromatogram shown.
- US synthesis and finishing, so the chain of custody is documented end to end.
- Cold-chain shipping for lyophilized material, so the product arrives stable.
Peptide Technologies meets each of these and shows the live competitor price on every product page. See how our pricing compares →
FAQ
What is Dihexa?
Dihexa is an angiotensin-IV-derived peptidomimetic studied in synaptogenesis and HGF/c-Met signaling research. It is supplied as a research chemical for laboratory use only.
Is Dihexa legal to buy for research?
Dihexa is sold by Peptide Technologies for laboratory research use only (RUO). It is not an approved drug, dietary supplement, cosmetic, or food. Buyers must affirm research use and accept the Terms of Sale at checkout. Not for use in humans or animals.
Is Dihexa FDA approved?
No. Dihexa is not approved by the FDA and is not intended to diagnose, mitigate, or prevent any condition. It is supplied strictly as a research chemical for laboratory use only.
How is Dihexa verified?
Research-grade Dihexa is verified by RP-HPLC for purity, by mass spectrometry for identity, and — where applicable — by an LAL endotoxin assay, all reported on a lot-specific third-party Certificate of Analysis.
Where can I buy Dihexa for research?
You can buy Dihexa online directly from Peptide Technologies at peptidetech.is, with a third-party COA, cold-chain shipping, and lot traceability on every batch. View the Dihexa product page →