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Peptides

What Is DSIP? A Research Peptide Overview

DSIP (delta sleep-inducing peptide) is a nonapeptide studied in sleep-model and neuropeptide research. Here is what it is and how to verify it.

Peptech Lab·Jul 5, 2026
DSIPdelta sleep-inducing peptideneuropeptideresearch peptides
What Is DSIP? A Research Peptide Overview
Research use only. Not for human or animal consumption. All products and content are for laboratory research purposes only.

Research use only. Not for use in humans or animals. All products and information on this site are provided strictly for in-vitro laboratory research purposes and are supplied as research chemicals only.

What Is DSIP? A Research Peptide Overview

DSIP (delta sleep-inducing peptide) is a naturally occurring nonapeptide first identified in neuroscience research on sleep-related brain activity. It is studied as a neuropeptide in model systems. This overview covers what DSIP is, what researchers study it for, and how to verify research-grade material.

DSIP at a glance

| Property | Value |

| --- | --- |

| Name | DSIP (delta sleep-inducing peptide) |

| Sequence | Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu (nonapeptide) |

| Molecular formula | C₃₅H₄₈N₁₀O₁₅ |

| Appearance | White lyophilized powder |

| Research area | Sleep models, neuropeptide signaling (in vitro / non-clinical) |

| Intended use | Laboratory research only |

Research background

DSIP was first isolated in neuroscience research investigating factors associated with delta-wave brain activity. It is a small, amphoteric nonapeptide that has been used as a reference neuropeptide in a range of model systems studying circadian and neuroendocrine signaling. Peptide Technologies supplies DSIP as a research chemical for that laboratory context only.

What DSIP is studied for

In laboratory research (cell-culture and non-clinical model systems), DSIP is studied for its role in:

  • Sleep-model research — neuropeptide activity in circadian and delta-wave model systems.
  • Neuroendocrine signaling — interactions with stress- and hormone-axis pathways in vitro.
  • Peptide-stability research — behavior of a small amphoteric nonapeptide in solution.

All of this is laboratory research; DSIP offered here is a research chemical only, supplied for in-vitro and non-clinical study.

How research-grade DSIP is verified

Every batch that ships from a credible US supplier should arrive with a third-party Certificate of Analysis (COA) for that exact lot. Peptide Technologies publishes a COA on every batch and ties it to a QR code on the vial. A complete COA reports:

  1. Identity — mass spectrometry (ESI-MS) confirming the observed mass matches the theoretical mass of the target compound.
  2. Purity — reverse-phase HPLC, reported as percent peak area (typically at 220 nm). Research-grade material is ≥98–99% by area.
  3. Net content — gravimetric confirmation the vial holds the stated mass within tolerance.
  4. Endotoxin — LAL assay below research thresholds, where applicable.

If a vendor cannot show you a lot-specific COA, you cannot verify what is in the vial. Browse the public COA library →

How to source research-grade material

For laboratory research, sourcing quality comes down to a few checks:

  • Lot-specific COA from an accredited, independent laboratory — not a generic marketing PDF.
  • HPLC purity ≥98% by peak area, with the chromatogram shown.
  • US synthesis and finishing, so the chain of custody is documented end to end.
  • Cold-chain shipping for lyophilized material, so the product arrives stable.

Peptide Technologies meets each of these and shows the live competitor price on every product page. See how our pricing compares →

FAQ

What is DSIP?

DSIP is a nonapeptide (delta sleep-inducing peptide) studied in sleep-model and neuropeptide research. It is supplied as a research chemical for laboratory use only.

Is DSIP legal to buy for research?

DSIP is sold by Peptide Technologies for laboratory research use only (RUO). It is not an approved drug, dietary supplement, cosmetic, or food. Buyers must affirm research use and accept the Terms of Sale at checkout. Not for use in humans or animals.

Is DSIP FDA approved?

No. DSIP is not approved by the FDA and is not intended to diagnose, mitigate, or prevent any condition. It is supplied strictly as a research chemical for laboratory use only.

How is DSIP verified?

Research-grade DSIP is verified by RP-HPLC for purity, by mass spectrometry for identity, and — where applicable — by an LAL endotoxin assay, all reported on a lot-specific third-party Certificate of Analysis.

Where can I buy DSIP for research?

You can buy DSIP online directly from Peptide Technologies at peptidetech.is, with a third-party COA, cold-chain shipping, and lot traceability on every batch. View the DSIP product page →

Further reading

Buy research-grade DSIP from Peptide Technologies →