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DSIP: molecular data, studies & sources
DSIP is catalogued here as a research compound. This profile brings together the molecular source record, selected indexed publications and available supplier comparisons. Evidence for a named substance does not authenticate a commercial product.
Compiled by PeptideTech Editors · Sources checked · Selected bibliography, not a systematic review
Molecular formula, weight & structure
- Molecular formula (MF)
- C35H48N10O15
- Molecular weight (MW)
- 848.8 g/mol
- PubChem compound ID
- 68816
- Record title
- Delta Sleep-Inducing Peptide
Values describe the selected PubChem molecular entity. Counterions, salt forms, hydration and sequence changes can alter the supplied material. Confirm the exact identity against the supplier specification.
Source: PubChem CID 68816 · retrieved 2026-09-21
Chemical identifiers and source data
- IUPAC name
- (2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-[[(2S)-2-amino-3-(1H-indol-3-yl)propanoyl]amino]propanoyl]amino]acetyl]amino]acetyl]amino]-3-carboxypropanoyl]amino]propanoyl]amino]-3-hydroxypropanoyl]amino]acetyl]amino]pentanedioic acid
- InChIKey
- ZRZROXNBKJAOKB-GFVHOAGBSA-N
- SMILES
- C[C@@H](C(=O)NCC(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)O)NC(=O)[C@H](CC1=CNC2=CC=CC=C21)N
Identifiers & sequence
- PubChem CID
- 68816
- CAS Registry Number
- 62568-57-4via ChemIDplus, EPA DSSTox, FDA GSRS
- FDA UNII
- YN28Z5YZ73
- ChEMBL ID
- CHEMBL2104403
- InChIKey
- ZRZROXNBKJAOKB-GFVHOAGBSA-N
- Wikidata
- Q27294600
Other names and development codes: Emideltide
Peptide sequence · 9 residues (one-letter code; X marks a residue without a one-letter code)
WAGGDASGE
Condensed notation with terminal groups and non-standard residues
H-Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu-OH
Source: PubChem Biologic Line Notation. A reference sequence for the record, not an analysis of a supplied batch.
CAS numbers are published only from ChemIDplus, EPA DSSTox or the FDA Global Substance Registration System; UNII codes are confirmed in FDA GSRS by structure, sequence or exact name. Checked 2026-10-07.
Calculated molecular descriptors
| Monoisotopic (exact) mass | 848.3301 Da |
|---|---|
| Heavy atoms | 60 |
| Hydrogen-bond donors | 14 |
| Hydrogen-bond acceptors | 13 |
| Rotatable bonds | 25 |
| Topological polar surface area | 406.7 Ų |
| Calculated logP (Crippen) | -5.73 |
| Rings | 2 |
| Stereocenters | 6 |
| Formal charge | 0 |
Computed with RDKit from the published SMILES (Crippen logP, topological polar surface area). Calculated descriptors are not measured properties of a supplied batch.
US regulatory status & drug development
Drugs@FDA lists no NDA, BLA or ANDA with emideltide as an active ingredient (names searched: EMIDELTIDE, DELTA SLEEP-INDUCING PEPTIDE; checked October 7, 2026). Research-labelled DSIP listings are not FDA-approved drugs.
An FDA approval covers a defined medicine, formulation and labelled use. It does not extend to research-labelled material sold under the same compound name. Identity basis: INN emideltide and the name delta sleep-inducing peptide were searched.
Source: Drugs@FDA via openFDA (active-ingredient search for EMIDELTIDE, DELTA SLEEP-INDUCING PEPTIDE) · checked . openFDA data are not intended for clinical decisions.
Drug development record (ChEMBL)
Harmonized drug-development record from ChEMBL. The highest clinical stage is the furthest stage reached, as recorded by ChEMBL; it can lag regulatory approvals, and it is not an approval of a research-supplier product.
- ChEMBL ID
- CHEMBL2104403
- Modality
- Protein / peptide
- Highest clinical stage
- Phase 2
- Record name
- EMIDELTIDE
Synonyms, codes and trade names
- Synonyms and development codes
- Emideltide
Identity check: Identical standard InChIKey to the PubChem record. Source: ChEMBL CHEMBL2104403 (EMBL-EBI, CC BY-SA 3.0) · retrieved 2026-10-07
Registered clinical trials
Studies registered on ClinicalTrials.gov that list Delta sleep-inducing peptide as an intervention. Studies that only measure the molecule as a biomarker, or use it only as a comparator or background arm for another drug, are excluded. A registration describes a planned or completed protocol; it does not report a result. Active studies are listed first.
No registered study naming this compound was matched. This is a documented gap in registry coverage, not proof that no study exists.
Registry check 2026-10-01 · Run this search on ClinicalTrials.gov
Human intervention studies
Selected studies in which participants received Delta sleep-inducing peptide, with their indexed or reviewed study type. Check the original article for the formulation, population and controls. Studies that only measured the molecule, or used it as a comparator, are listed separately below and are not counted as intervention studies.
- Human study · PubMed trial index Compound given to participants
Effects of delta sleep-inducing peptide on sleep of chronic insomniac patients. A double-blind study.
Bes F, Hofman W, Schuur J et al. · Neuropsychobiology · 1992
PMID 1299794 · DOI: 10.1159/000118919
- Human study · PubMed trial index Compound given to participants
Effects of delta-sleep-inducing peptide on 24-hour sleep-wake behaviour in severe chronic insomnia.
Schneider-Helmert D · European neurology · 1987
PMID 3622582 · DOI: 10.1159/000116143
- Human study · PubMed trial index Compound given to participants
Delta sleep-inducing peptide administration does not influence growth hormone and prolactin secretion in normal women.
Giusti M, Carraro A, Porcella E et al. · Psychoneuroendocrinology · 1993
PMID 8475226 · DOI: 10.1016/0306-4530(93)90057-r
Preclinical research, reviews & other publications
Animal studies, laboratory experiments, reviews and other indexed papers answer different questions. A review is secondary evidence; a case report does not estimate how often an outcome occurs.
- Review · secondary evidence
Delta sleep-inducing peptide.
Pollard BJ, Pomfrett CJ · European journal of anaesthesiology · 2001
PMID 11437870 · DOI: 10.1046/j.1365-2346.2001.00917.x
- Review · secondary evidence
Delta-sleep-inducing peptide (DSIP): a review.
Graf MV, Kastin AJ · Neuroscience and biobehavioral reviews · 1984
PMID 6145137 · DOI: 10.1016/0149-7634(84)90022-8
DSIP supplier sources
Scientific sources describe molecules and experiments. The commercial links below identify recorded supplier packages. A publication or chemical database entry does not verify the seller, purity, sterility or contents of a lot. Some links are affiliate links; see our disclosure.
DSIP for sale: compare prices, sizes and forms from every tracked supplier →
| Supplier | Recorded packages | Example source listing |
|---|---|---|
| American PeptidesUSD | 5mg Vial1 recorded offers | 5mg Vial · $55.00Checked Nov 6, 2026Supplier listing, DSIP 5mg Vial, American Peptides, opens in a new tab |
| Blank PeptidesUSD | 10mg Vial1 recorded offers | 10mg Vial · $65.00Stale observation · Checked Sep 30, 2026Supplier listing, DSIP 10mg Vial, Blank Peptides, opens in a new tab |
| Amino ClubUSD | 5mg Vial · 15mg Spray2 recorded offers | 5mg Vial · $29.99Stale observation · Checked Oct 14, 2026Supplier listing, DSIP 5mg Vial, Amino Club, opens in a new tab |
| Nova Peptide SupplyUSD | 5mg Vial · 10mg Spray2 recorded offers | 5mg Vial · $34.99Checked Nov 6, 2026Supplier listing, DSIP 5mg Vial, Nova Peptide Supply, opens in a new tab |
| Amino USAUSD | 5mg Vial1 recorded offers | 5mg Vial · $45.00Checked Nov 6, 2026Supplier listing, DSIP 5mg Vial, Amino USA, opens in a new tab |
| Cenexa LabsUSD | 15mg Vial · 5mg Vial · 10mg Spray3 recorded offers | 15mg Vial · $99.99Checked Nov 6, 2026Supplier listing, DSIP 15mg Vial, Cenexa Labs, opens in a new tab |
| LA PeptidesUSD | 5mg Vial1 recorded offers | 5mg Vial · $29.99Checked Nov 3, 2026Supplier listing, DSIP 5mg Vial, LA Peptides, opens in a new tab |
Reference sources & further reading
- PubChem compound record 68816 — chemical identity and structure.
- ChEMBL drug record CHEMBL2104403 — development stage, mechanism and synonyms.
- FDA Global Substance Registration System: UNII YN28Z5YZ73 — substance identity, names and codes.
- Wikipedia: Delta-sleep-inducing peptide — Background encyclopedia; not a primary clinical source.
The citations above link directly to publication records. Encyclopedia links are background reading and are not used to establish clinical effectiveness.
Search for additional research
These links run searches; their results have not been individually reviewed and can include unrelated compounds.
Research information is not a dosing guide or a recommendation for personal use. Study findings are specific to the formulation, population and methods tested. Read our source and correction policy.