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GHRP-2: molecular data, studies & sources
GHRP-2 is catalogued here as a research compound. This profile brings together the molecular source record, selected indexed publications and available supplier comparisons. Evidence for a named substance does not authenticate a commercial product.
Compiled by PeptideTech Editors · Sources checked · Selected bibliography, not a systematic review
Molecular formula, weight & structure
- Molecular formula (MF)
- C45H55N9O6
- Molecular weight (MW)
- 818.0 g/mol
- PubChem compound ID
- 6918245
- Record title
- Pralmorelin
Values describe the selected PubChem molecular entity. Counterions, salt forms, hydration and sequence changes can alter the supplied material. Confirm the exact identity against the supplier specification.
Source: PubChem CID 6918245 · retrieved 2026-09-21

Chemical identifiers and source data
- IUPAC name
- (2S)-6-amino-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2R)-2-aminopropanoyl]amino]-3-naphthalen-2-ylpropanoyl]amino]propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-phenylpropanoyl]amino]hexanamide
- InChIKey
- HRNLPPBUBKMZMT-RDRUQFPZSA-N
- SMILES
- C[C@H](C(=O)N[C@H](CC1=CC2=CC=CC=C2C=C1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC3=CNC4=CC=CC=C43)C(=O)N[C@H](CC5=CC=CC=C5)C(=O)N[C@@H](CCCCN)C(=O)N)N
Identifiers & sequence
- PubChem CID
- 6918245
- CAS Registry Number
- 158861-67-7via ChemIDplus, EPA DSSTox, FDA GSRS
- FDA UNII
- E6S6E1F19M
- ChEMBL ID
- CHEMBL106593
- InChIKey
- HRNLPPBUBKMZMT-RDRUQFPZSA-N
- Wikidata
- Q21098924
Other names and development codes: KP-102
Peptide sequence · 6 residues (one-letter code; X marks a residue without a one-letter code)
AXAWFK
Condensed notation with terminal groups and non-standard residues
H-D-Ala-D-2Nal-Ala-Trp-D-Phe-Lys-NH2
Source: PubChem Biologic Line Notation. A reference sequence for the record, not an analysis of a supplied batch.
CAS numbers are published only from ChemIDplus, EPA DSSTox or the FDA Global Substance Registration System; UNII codes are confirmed in FDA GSRS by structure, sequence or exact name. Checked 2026-10-07.
Calculated molecular descriptors
| Monoisotopic (exact) mass | 817.4275 Da |
|---|---|
| Heavy atoms | 60 |
| Hydrogen-bond donors | 9 |
| Hydrogen-bond acceptors | 8 |
| Rotatable bonds | 21 |
| Topological polar surface area | 256.4 Ų |
| Calculated logP (Crippen) | 1.75 |
| Rings | 5 |
| Stereocenters | 6 |
| Formal charge | 0 |
Computed with RDKit from the published SMILES (Crippen logP, topological polar surface area). Calculated descriptors are not measured properties of a supplied batch.
US regulatory status & drug development
Drugs@FDA lists no NDA, BLA or ANDA with pralmorelin as an active ingredient (names searched: PRALMORELIN, PRALMORELIN DIHYDROCHLORIDE, GHRP-2; checked October 7, 2026). Research-labelled GHRP-2 listings are not FDA-approved drugs.
An FDA approval covers a defined medicine, formulation and labelled use. It does not extend to research-labelled material sold under the same compound name. Identity basis: INN pralmorelin, its dihydrochloride and the code GHRP-2 were searched.
Source: Drugs@FDA via openFDA (active-ingredient search for PRALMORELIN, PRALMORELIN DIHYDROCHLORIDE, GHRP-2) · checked . openFDA data are not intended for clinical decisions.
Drug development record (ChEMBL)
Harmonized drug-development record from ChEMBL. The highest clinical stage is the furthest stage reached, as recorded by ChEMBL; it can lag regulatory approvals, and it is not an approval of a research-supplier product.
- ChEMBL ID
- CHEMBL106593
- Modality
- Protein / peptide
- Highest clinical stage
- Phase 2
- Record name
- PRALMORELIN
Synonyms, codes and trade names
- Synonyms and development codes
- KP-102 · Pralmorelin
Identity check: Identical standard InChIKey to the PubChem record. Source: ChEMBL CHEMBL106593 (EMBL-EBI, CC BY-SA 3.0) · retrieved 2026-10-07
Registered clinical trials
Studies registered on ClinicalTrials.gov that list GHRP-2 as an intervention. Studies that only measure the molecule as a biomarker, or use it only as a comparator or background arm for another drug, are excluded. A registration describes a planned or completed protocol; it does not report a result. Active studies are listed first.
No registered study naming this compound was matched. This is a documented gap in registry coverage, not proof that no study exists.
Registry check 2026-10-01 · Run this search on ClinicalTrials.gov
Human intervention studies
Selected studies in which participants received GHRP-2, with their indexed or reviewed study type. Check the original article for the formulation, population and controls. Studies that only measured the molecule, or used it as a comparator, are listed separately below and are not counted as intervention studies.
- Human study · PubMed trial index Compound given to participants
GHRP-2, GHRH and SRIF interrelationships during chronic administration of GHRP-2 to humans.
Bowers CY, Granda-Ayala R · Journal of pediatric endocrinology & metabolism : JPEM · 1996
PMID 8887169
- Human study · PubMed trial index Compound given to participants
The combined administration of GH-releasing peptide-2 (GHRP-2), TRH and GnRH to men with prolonged critical illness evokes superior endocrine and metabolic effects compared to treatment with GHRP-2 alone.
Van den Berghe G, Baxter RC, Weekers F et al. · Clinical endocrinology · 2002
PMID 12030918 · DOI: 10.1046/j.1365-2265.2002.01255.x
Preclinical research, reviews & other publications
Animal studies, laboratory experiments, reviews and other indexed papers answer different questions. A review is secondary evidence; a case report does not estimate how often an outcome occurs.
- Review · secondary evidence
Pralmorelin: GHRP 2, GPA 748, growth hormone-releasing peptide 2, KP-102 D, KP-102 LN, KP-102D, KP-102LN.
· Drugs in R&D · 2004
PMID 15230633 · DOI: 10.2165/00126839-200405040-00011
- Research publication · design requires review
Determination of growth hormone secretagogue pralmorelin (GHRP-2) and its metabolite in human urine by liquid chromatography/electrospray ionization tandem mass spectrometry.
Okano M, Sato M, Ikekita A et al. · Rapid communications in mass spectrometry : RCM · 2010
PMID 20552695 · DOI: 10.1002/rcm.4619
- Preclinical / laboratory research
Pharmacological characteristics of KP-102 (GHRP-2), a potent growth hormone-releasing peptide.
Doi N, Hirotani C, Ukai K et al. · Arzneimittel-Forschung · 2004
PMID 15646370 · DOI: 10.1055/s-0031-1297041
- Research publication · design requires review
Determination of growth hormone releasing peptides metabolites in human urine after nasal administration of GHRP-1, GHRP-2, GHRP-6, Hexarelin, and Ipamorelin.
Semenistaya E, Zvereva I, Thomas A et al. · Drug testing and analysis · 2015
PMID 25869809 · DOI: 10.1002/dta.1787
- Research publication · design requires review
Growth hormone releasing peptide-2 (GHRP-2), like ghrelin, increases food intake in healthy men.
Laferrère B, Abraham C, Russell CD et al. · The Journal of clinical endocrinology and metabolism · 2005
PMID 15699539 · DOI: 10.1210/jc.2004-1719
- Research publication · design requires review
Detection of GHRP-2 and GHRP-6 in urine samples from athletes.
Cox HD, Hughes CM, Eichner D et al. · Drug testing and analysis · 2015
PMID 25809000 · DOI: 10.1002/dta.1791
GHRP-2 supplier sources
Scientific sources describe molecules and experiments. The commercial links below identify recorded supplier packages. A publication or chemical database entry does not verify the seller, purity, sterility or contents of a lot. Some links are affiliate links; see our disclosure.
GHRP-2 for sale: compare prices, sizes and forms from every tracked supplier →
| Supplier | Recorded packages | Example source listing |
|---|---|---|
| Amino USAUSD | 5mg Vial1 recorded offers | 5mg Vial · $20.00Checked Nov 6, 2026Supplier listing, GHRP-2 5mg Vial, Amino USA, opens in a new tab |
| Cenexa LabsUSD | 5mg Vial · 10mg Vial2 recorded offers | 5mg Vial · $24.99Checked Nov 6, 2026Supplier listing, GHRP-2 5mg Vial, Cenexa Labs, opens in a new tab |
Reference sources & further reading
- PubChem compound record 6918245 — chemical identity and structure.
- ChEMBL drug record CHEMBL106593 — development stage, mechanism and synonyms.
- FDA Global Substance Registration System: UNII E6S6E1F19M — substance identity, names and codes.
- Wikipedia: Pralmorelin — Background encyclopedia; not a primary clinical source.
The citations above link directly to publication records. Encyclopedia links are background reading and are not used to establish clinical effectiveness.
Search for additional research
These links run searches; their results have not been individually reviewed and can include unrelated compounds.
Research information is not a dosing guide or a recommendation for personal use. Study findings are specific to the formulation, population and methods tested. Read our source and correction policy.
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