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Home / Research library / GHRP-2

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GHRP-2: molecular data, studies & sources

GHRP-2 is catalogued here as a research compound. This profile brings together the molecular source record, selected indexed publications and available supplier comparisons. Evidence for a named substance does not authenticate a commercial product.

Compiled by PeptideTech Editors · Sources checked · Selected bibliography, not a systematic review

Molecular formula, weight & structure

Molecular formula (MF)
C45H55N9O6
Molecular weight (MW)
818.0 g/mol
PubChem compound ID
6918245
Record title
Pralmorelin

Values describe the selected PubChem molecular entity. Counterions, salt forms, hydration and sequence changes can alter the supplied material. Confirm the exact identity against the supplier specification.

Source: PubChem CID 6918245 · retrieved 2026-09-21

2D molecular structure for GHRP-2, PubChem CID 6918245
2D depiction from PubChem. Open to inspect the full image. This drawing represents the selected record, not a vendor batch test.
Chemical identifiers and source data
IUPAC name
(2S)-6-amino-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2R)-2-aminopropanoyl]amino]-3-naphthalen-2-ylpropanoyl]amino]propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-phenylpropanoyl]amino]hexanamide
InChIKey
HRNLPPBUBKMZMT-RDRUQFPZSA-N
SMILES
C[C@H](C(=O)N[C@H](CC1=CC2=CC=CC=C2C=C1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC3=CNC4=CC=CC=C43)C(=O)N[C@H](CC5=CC=CC=C5)C(=O)N[C@@H](CCCCN)C(=O)N)N
Machine-readable PubChem source

Identifiers & sequence

PubChem CID
6918245
CAS Registry Number
158861-67-7via ChemIDplus, EPA DSSTox, FDA GSRS
FDA UNII
E6S6E1F19M
ChEMBL ID
CHEMBL106593
InChIKey
HRNLPPBUBKMZMT-RDRUQFPZSA-N
Wikidata
Q21098924

Other names and development codes: KP-102

Peptide sequence · 6 residues (one-letter code; X marks a residue without a one-letter code)

AXAWFK

Condensed notation with terminal groups and non-standard residues

H-D-Ala-D-2Nal-Ala-Trp-D-Phe-Lys-NH2

Source: PubChem Biologic Line Notation. A reference sequence for the record, not an analysis of a supplied batch.

CAS numbers are published only from ChemIDplus, EPA DSSTox or the FDA Global Substance Registration System; UNII codes are confirmed in FDA GSRS by structure, sequence or exact name. Checked 2026-10-07.

Calculated molecular descriptors
Monoisotopic (exact) mass817.4275 Da
Heavy atoms60
Hydrogen-bond donors9
Hydrogen-bond acceptors8
Rotatable bonds21
Topological polar surface area256.4 Ų
Calculated logP (Crippen)1.75
Rings5
Stereocenters6
Formal charge0

Computed with RDKit from the published SMILES (Crippen logP, topological polar surface area). Calculated descriptors are not measured properties of a supplied batch.

US regulatory status & drug development

Drugs@FDA lists no NDA, BLA or ANDA with pralmorelin as an active ingredient (names searched: PRALMORELIN, PRALMORELIN DIHYDROCHLORIDE, GHRP-2; checked October 7, 2026). Research-labelled GHRP-2 listings are not FDA-approved drugs.

An FDA approval covers a defined medicine, formulation and labelled use. It does not extend to research-labelled material sold under the same compound name. Identity basis: INN pralmorelin, its dihydrochloride and the code GHRP-2 were searched.

Source: Drugs@FDA via openFDA (active-ingredient search for PRALMORELIN, PRALMORELIN DIHYDROCHLORIDE, GHRP-2) · checked . openFDA data are not intended for clinical decisions.

Drug development record (ChEMBL)

Harmonized drug-development record from ChEMBL. The highest clinical stage is the furthest stage reached, as recorded by ChEMBL; it can lag regulatory approvals, and it is not an approval of a research-supplier product.

ChEMBL ID
CHEMBL106593
Modality
Protein / peptide
Highest clinical stage
Phase 2
Record name
PRALMORELIN
Synonyms, codes and trade names
Synonyms and development codes
KP-102 · Pralmorelin

Identity check: Identical standard InChIKey to the PubChem record. Source: ChEMBL CHEMBL106593 (EMBL-EBI, CC BY-SA 3.0) · retrieved 2026-10-07

Registered clinical trials

Studies registered on ClinicalTrials.gov that list GHRP-2 as an intervention. Studies that only measure the molecule as a biomarker, or use it only as a comparator or background arm for another drug, are excluded. A registration describes a planned or completed protocol; it does not report a result. Active studies are listed first.

No registered study naming this compound was matched. This is a documented gap in registry coverage, not proof that no study exists.

Registry check 2026-10-01 · Run this search on ClinicalTrials.gov

Human intervention studies

Selected studies in which participants received GHRP-2, with their indexed or reviewed study type. Check the original article for the formulation, population and controls. Studies that only measured the molecule, or used it as a comparator, are listed separately below and are not counted as intervention studies.

  1. Human study · PubMed trial index Compound given to participants

    GHRP-2, GHRH and SRIF interrelationships during chronic administration of GHRP-2 to humans.

    Bowers CY, Granda-Ayala R · Journal of pediatric endocrinology & metabolism : JPEM · 1996

    PMID 8887169

  2. Human study · PubMed trial index Compound given to participants

    The combined administration of GH-releasing peptide-2 (GHRP-2), TRH and GnRH to men with prolonged critical illness evokes superior endocrine and metabolic effects compared to treatment with GHRP-2 alone.

    Van den Berghe G, Baxter RC, Weekers F et al. · Clinical endocrinology · 2002

    PMID 12030918 · DOI: 10.1046/j.1365-2265.2002.01255.x

Preclinical research, reviews & other publications

Animal studies, laboratory experiments, reviews and other indexed papers answer different questions. A review is secondary evidence; a case report does not estimate how often an outcome occurs.

  1. Review · secondary evidence

    Pralmorelin: GHRP 2, GPA 748, growth hormone-releasing peptide 2, KP-102 D, KP-102 LN, KP-102D, KP-102LN.

    · Drugs in R&D · 2004

    PMID 15230633 · DOI: 10.2165/00126839-200405040-00011

  2. Research publication · design requires review

    Determination of growth hormone secretagogue pralmorelin (GHRP-2) and its metabolite in human urine by liquid chromatography/electrospray ionization tandem mass spectrometry.

    Okano M, Sato M, Ikekita A et al. · Rapid communications in mass spectrometry : RCM · 2010

    PMID 20552695 · DOI: 10.1002/rcm.4619

  3. Preclinical / laboratory research

    Pharmacological characteristics of KP-102 (GHRP-2), a potent growth hormone-releasing peptide.

    Doi N, Hirotani C, Ukai K et al. · Arzneimittel-Forschung · 2004

    PMID 15646370 · DOI: 10.1055/s-0031-1297041

  4. Research publication · design requires review

    Determination of growth hormone releasing peptides metabolites in human urine after nasal administration of GHRP-1, GHRP-2, GHRP-6, Hexarelin, and Ipamorelin.

    Semenistaya E, Zvereva I, Thomas A et al. · Drug testing and analysis · 2015

    PMID 25869809 · DOI: 10.1002/dta.1787

  5. Research publication · design requires review

    Growth hormone releasing peptide-2 (GHRP-2), like ghrelin, increases food intake in healthy men.

    Laferrère B, Abraham C, Russell CD et al. · The Journal of clinical endocrinology and metabolism · 2005

    PMID 15699539 · DOI: 10.1210/jc.2004-1719

  6. Research publication · design requires review

    Detection of GHRP-2 and GHRP-6 in urine samples from athletes.

    Cox HD, Hughes CM, Eichner D et al. · Drug testing and analysis · 2015

    PMID 25809000 · DOI: 10.1002/dta.1791

GHRP-2 supplier sources

Scientific sources describe molecules and experiments. The commercial links below identify recorded supplier packages. A publication or chemical database entry does not verify the seller, purity, sterility or contents of a lot. Some links are affiliate links; see our disclosure.

GHRP-2 for sale: compare prices, sizes and forms from every tracked supplier →

SupplierRecorded packagesExample source listing
Amino USAUSD5mg Vial1 recorded offers5mg Vial · $20.00Checked Nov 6, 2026Supplier listing, GHRP-2 5mg Vial, Amino USA, opens in a new tab
Cenexa LabsUSD5mg Vial · 10mg Vial2 recorded offers5mg Vial · $24.99Checked Nov 6, 2026Supplier listing, GHRP-2 5mg Vial, Cenexa Labs, opens in a new tab

Reference sources & further reading

The citations above link directly to publication records. Encyclopedia links are background reading and are not used to establish clinical effectiveness.

Search for additional research

These links run searches; their results have not been individually reviewed and can include unrelated compounds.

Research information is not a dosing guide or a recommendation for personal use. Study findings are specific to the formulation, population and methods tested. Read our source and correction policy.

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