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Home / Research library / Bronchogen

Bioregulators · Peptides

Bronchogen: molecular data, studies & sources

Bronchogen appears in studies of DNA interactions, organotypic rat tissue cultures and cultured cells. These are preclinical experiments, including human-derived cells outside the body; they are not clinical trials in patients. The literature also contains a sequence-order discrepancy, explained in the molecular identity notes.

Overview sources: PMID 21240358 · PMID 17152728 · PMID 22808515

Compiled by PeptideTech Editors · Sources checked · Selected bibliography, not a systematic review

Molecular formula, weight & structure

Molecular formula (MF)
C18H30N4O9
Molecular weight (MW)
446.5 g/mol
PubChem compound ID
11690869
Record title
Bronchogen

The displayed PubChem structure represents Ala-Glu-Asp-Leu (AEDL), also reported in PMID 22808515. The title of PMID 21240358 instead writes Ala-Asp-Glu-Leu. Those sequence orders are not interchangeable; verify the exact experimental or supplier sequence.

Source: PubChem CID 11690869 · retrieved 2026-09-21

2D molecular structure for Bronchogen, PubChem CID 11690869
2D depiction from PubChem. Open to inspect the full image. This drawing represents the selected record, not a vendor batch test.
Chemical identifiers and source data
IUPAC name
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-aminopropanoyl]amino]-4-carboxybutanoyl]amino]-3-carboxypropanoyl]amino]-4-methylpentanoic acid
InChIKey
OFZRHTIWKZWPQF-BJDJZHNGSA-N
SMILES
C[C@@H](C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)O)N
Machine-readable PubChem source

Identifiers & sequence

PubChem CID
11690869
InChIKey
OFZRHTIWKZWPQF-BJDJZHNGSA-N

Peptide sequence · 4 residues (one-letter code; X marks a residue without a one-letter code)

AEDL

Condensed notation with terminal groups and non-standard residues

H-Ala-Glu-Asp-Leu-OH

Source: PubChem Biologic Line Notation. A reference sequence for the record, not an analysis of a supplied batch.

Calculated molecular descriptors
Monoisotopic (exact) mass446.2013 Da
Heavy atoms31
Hydrogen-bond donors7
Hydrogen-bond acceptors7
Rotatable bonds14
Topological polar surface area225.2 Ų
Calculated logP (Crippen)-1.74
Rings0
Stereocenters4
Formal charge0

Computed with RDKit from the published SMILES (Crippen logP, topological polar surface area). Calculated descriptors are not measured properties of a supplied batch.

Registered clinical trials

Studies registered on ClinicalTrials.gov that list Bronchogen as an intervention. Studies that only measure the molecule as a biomarker, or use it only as a comparator or background arm for another drug, are excluded. A registration describes a planned or completed protocol; it does not report a result. Active studies are listed first.

No registered study naming this compound was matched. This is a documented gap in registry coverage, not proof that no study exists.

Registry check 2026-10-01 · Run this search on ClinicalTrials.gov

Human intervention studies

Selected studies in which participants received Bronchogen, with their indexed or reviewed study type. Check the original article for the formulation, population and controls. Studies that only measured the molecule, or used it as a comparator, are listed separately below and are not counted as intervention studies.

No human study that administered this compound was retained in this selected bibliography. This is a documented evidence gap in our selection, not proof that no study exists.

    Preclinical research, reviews & other publications

    Animal studies, laboratory experiments, reviews and other indexed papers answer different questions. A review is secondary evidence; a case report does not estimate how often an outcome occurs.

    1. Preclinical / laboratory research

      Effect of the peptide bronchogen (Ala-Asp-Glu-Leu) on DNA thermostability.

      Monaselidze JR, Khavinson VKh, Gorgoshidze MZ et al. · Bulletin of experimental biology and medicine · 2011

      Laboratory DNA thermostability experiment. The sequence order in this title differs from the selected PubChem record; see the identity note.

      PMID 21240358 · DOI: 10.1007/s10517-011-1146-x

    2. Preclinical / laboratory research

      [The tissue-specific effect of synthetic peptides-biologic regulators in organotypic tissues culture in young and old rats].

      Zakutskiĭ AN, Chalisova NI, Ryzhak GA et al. · Advances in gerontology = Uspekhi gerontologii · 2006

      Organotypic tissue cultures from young and aged rats. Tissue-culture responses do not demonstrate patient benefit.

      PMID 17152728

    3. Preclinical / laboratory research

      Peptides tissue-specifically stimulate cell differentiation during their aging.

      Khavinson VKh, Linkova NS, Polyakova VO et al. · Bulletin of experimental biology and medicine · 2012

      Experiments in cultured human-derived cells. Human cell culture is not a clinical trial in people.

      PMID 22808515 · DOI: 10.1007/s10517-012-1664-1

    4. Research publication · design requires review

      Short Exogenous Peptides Regulate Expression of CLE, KNOX1, and GRF Family Genes in Nicotiana tabacum.

      Fedoreyeva LI, Dilovarova TA, Ashapkin VV et al. · Biochemistry. Biokhimiia · 2017

      PMID 28371610 · DOI: 10.1134/S0006297917040149

    5. Preclinical / laboratory research

      Modulating Effect of Peptide Therapy on the Morphofunctional State of Bronchial Epithelium in Rats with Obstructive Lung Pathology.

      Kuzubova NA, Lebedeva ES, Dvorakovskaya IV et al. · Bulletin of experimental biology and medicine · 2015

      PMID 26468022 · DOI: 10.1007/s10517-015-3047-x

    6. Preclinical / laboratory research

      [ANTIINFLAMMATORY AND REGENERATIVE EFFECT OF PEPTIDE THERAPY IN THE MODEL OF OBSTRUCTIVE LUNG PATHOLOGY].

      Titova ON, Kuzubova NA, Lebedeva ES et al. · Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova · 2017

      PMID 30199201

    Bronchogen supplier sources

    Scientific sources describe molecules and experiments. The commercial links below identify recorded supplier packages. A publication or chemical database entry does not verify the seller, purity, sterility or contents of a lot. Some links are affiliate links; see our disclosure.

    Bronchogen for sale: compare prices, sizes and forms from every tracked supplier →

    SupplierRecorded packagesExample source listing
    Amino USAUSD20mg Vial1 recorded offers20mg Vial · $50.00Stale observation · Checked Oct 14, 2026Supplier listing, Bronchogen 20mg Vial, Amino USA, opens in a new tab
    Cenexa LabsUSD20mg Vial1 recorded offers20mg Vial · $54.99Checked Nov 6, 2026Supplier listing, Bronchogen 20mg Vial, Cenexa Labs, opens in a new tab

    Reference sources & further reading

    The citations above link directly to publication records. Encyclopedia links are background reading and are not used to establish clinical effectiveness.

    Search for additional research

    These links run searches; their results have not been individually reviewed and can include unrelated compounds.

    Research information is not a dosing guide or a recommendation for personal use. Study findings are specific to the formulation, population and methods tested. Read our source and correction policy.

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