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Enclomiphene: molecular data, studies & sources

Enclomiphene is catalogued here as a research compound. This profile brings together the molecular source record, selected indexed publications and available supplier comparisons. Evidence for a named substance does not authenticate a commercial product.

Compiled by PeptideTech Editors · Sources checked 2026-09-21 · Selected bibliography, not a systematic review

Molecular formula, weight & structure

Molecular formula (MF): C26H28ClNO
Molecular weight (MW): 406.0 g/mol
PubChem compound ID: 1548953
Record title: Enclomiphene

Values describe the selected PubChem molecular entity. Counterions, salt forms, hydration and sequence changes can alter the supplied material. Confirm the exact identity against the supplier specification.

Source: PubChem CID 1548953 · retrieved 2026-09-21

PubChem 2D molecular structure for Enclomiphene, CID 1548953 — 2D depiction from PubChem. Open to inspect the full image. This drawing represents the selected record, not a vendor batch test.

Chemical identifiers and source data

IUPAC name: 2-[4-[(E)-2-chloro-1,2-diphenylethenyl]phenoxy]-N,N-diethylethanamine
InChIKey: GKIRPKYJQBWNGO-OCEACIFDSA-N
SMILES: CCN(CC)CCOC1=CC=C(C=C1)/C(=C(\C2=CC=CC=C2)/Cl)/C3=CC=CC=C3

Machine-readable PubChem source

Human and clinical studies

Selected human-study records are shown with their indexed or reviewed study type. Check the original article for the intervention, formulation and controls; the molecule can also be a comparator or measured variable.

Human study · PubMed trial index
Oral enclomiphene citrate raises testosterone and preserves sperm counts in obese hypogonadal men, unlike topical testosterone: restoration instead of replacement.
Kim ED, McCullough A, Kaminetsky J et al. · BJU international · 2016
PMID 26496621 · DOI: 10.1111/bju.13337
Human study · PubMed trial index
Oral enclomiphene citrate stimulates the endogenous production of testosterone and sperm counts in men with low testosterone: comparison with testosterone gel.
Kaminetsky J, Werner M, Fontenot G et al. · The journal of sexual medicine · 2013
PMID 23530575 · DOI: 10.1111/jsm.12116
Human study · PubMed trial index
Enclomiphene citrate stimulates testosterone production while preventing oligospermia: a randomized phase II clinical trial comparing topical testosterone.
Wiehle RD, Fontenot GK, Wike J et al. · Fertility and sterility · 2014
PMID 25044085 · DOI: 10.1016/j.fertnstert.2014.06.004

Preclinical research, reviews & other publications

Animal studies, laboratory experiments, reviews and other indexed papers answer different questions. A review is secondary evidence; a case report does not estimate how often an outcome occurs.

Research publication · design requires review
Safety and efficacy of enclomiphene and clomiphene for hypogonadal men.
Saffati G, Kassab J, Orozco Rendon D et al. · Translational andrology and urology · 2024
PMID 39434750 · DOI: 10.21037/tau-24-238
Review · secondary evidence
Enclomiphene, an estrogen receptor antagonist for the treatment of testosterone deficiency in men.
Hill S, Arutchelvam V, Quinton R et al. · IDrugs : the investigational drugs journal · 2009
PMID 19204885

Enclomiphene supplier sources

Scientific sources describe molecules and experiments. The commercial links below identify recorded supplier packages. A publication or chemical database entry does not verify the seller, purity, sterility or contents of a lot. Some links are affiliate links; see our disclosure.

Compare all Enclomiphene sizes, forms and supplier prices →

Supplier	Recorded packages	Example source listing
Nova Peptide SupplyUSD	12.5mg×60 Capsules · 12.5mg-per-mL-30mL Solution2 recorded offers	12.5mg×60 Capsules · $99.99Checked Sep 16, 2026Supplier listing
Cenexa LabsUSD	12.5mg×60 Capsules1 recorded offers	12.5mg×60 Capsules · $79.99Checked Sep 16, 2026Supplier listing
Amino USAUSD	12.5mg-per-mL-30mL Solution1 recorded offers	12.5mg-per-mL-30mL Solution · $49.50Checked Sep 16, 2026Supplier listing

Reference sources & further reading

PubChem compound record 1548953 — chemical identity and structure.
Wikipedia: Enclomifene — Background encyclopedia; not a primary clinical source.

The citations above link directly to publication records. Encyclopedia links are background reading and are not used to establish clinical effectiveness.

Search for additional research

These links run searches; their results have not been individually reviewed and can include unrelated compounds.

Research information is not a dosing guide or a recommendation for personal use. Study findings are specific to the formulation, population and methods tested. Read our source and correction policy.