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Ipamorelin: molecular data, studies & sources

Ipamorelin is catalogued here as a research compound. This profile brings together the molecular source record, selected indexed publications and available supplier comparisons. Evidence for a named substance does not authenticate a commercial product.

Compiled by PeptideTech Editors · Sources checked · Selected bibliography, not a systematic review

Molecular formula, weight & structure

Molecular formula (MF)
C38H49N9O5
Molecular weight (MW)
711.9 g/mol
PubChem compound ID
9831659
Record title
Ipamorelin

Values describe the selected PubChem molecular entity. Counterions, salt forms, hydration and sequence changes can alter the supplied material. Confirm the exact identity against the supplier specification.

Source: PubChem CID 9831659 · retrieved 2026-09-21

2D molecular structure for Ipamorelin, PubChem CID 9831659
2D depiction from PubChem. Open to inspect the full image. This drawing represents the selected record, not a vendor batch test.
Chemical identifiers and source data
IUPAC name
(2S)-6-amino-2-[[(2R)-2-[[(2R)-2-[[(2S)-2-[(2-amino-2-methylpropanoyl)amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-naphthalen-2-ylpropanoyl]amino]-3-phenylpropanoyl]amino]hexanamide
InChIKey
NEHWBYHLYZGBNO-BVEPWEIPSA-N
SMILES
CC(C)(C(=O)N[C@@H](CC1=CN=CN1)C(=O)N[C@H](CC2=CC3=CC=CC=C3C=C2)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)N[C@@H](CCCCN)C(=O)N)N
Machine-readable PubChem source

Identifiers & sequence

PubChem CID
9831659
CAS Registry Number
170851-70-4via ChemIDplus, FDA GSRS
FDA UNII
Y9M3S784Z6
ChEMBL ID
CHEMBL58547
InChIKey
NEHWBYHLYZGBNO-BVEPWEIPSA-N
Wikidata
Q76414523

Other names and development codes: NNC 26-0161

Peptide sequence · 5 residues (one-letter code; X marks a residue without a one-letter code)

XHXFK

Condensed notation with terminal groups and non-standard residues

H-Aib-His-D-2Nal-D-Phe-Lys-NH2

Source: PubChem Biologic Line Notation. A reference sequence for the record, not an analysis of a supplied batch.

CAS numbers are published only from ChemIDplus, EPA DSSTox or the FDA Global Substance Registration System; UNII codes are confirmed in FDA GSRS by structure, sequence or exact name. Checked 2026-10-07.

Calculated molecular descriptors
Monoisotopic (exact) mass711.3857 Da
Heavy atoms52
Hydrogen-bond donors8
Hydrogen-bond acceptors8
Rotatable bonds19
Topological polar surface area240.2 Ų
Calculated logP (Crippen)0.88
Rings4
Stereocenters4
Formal charge0

Computed with RDKit from the published SMILES (Crippen logP, topological polar surface area). Calculated descriptors are not measured properties of a supplied batch.

US regulatory status & drug development

Drugs@FDA lists no NDA, BLA or ANDA with ipamorelin as an active ingredient (names searched: IPAMORELIN, IPAMORELIN ACETATE; checked October 7, 2026). Research-labelled Ipamorelin listings are not FDA-approved drugs.

An FDA approval covers a defined medicine, formulation and labelled use. It does not extend to research-labelled material sold under the same compound name. Identity basis: INN and its acetate salt were searched.

Source: Drugs@FDA via openFDA (active-ingredient search for IPAMORELIN, IPAMORELIN ACETATE) · checked . openFDA data are not intended for clinical decisions.

Drug development record (ChEMBL)

Harmonized drug-development record from ChEMBL. The highest clinical stage is the furthest stage reached, as recorded by ChEMBL; it can lag regulatory approvals, and it is not an approval of a research-supplier product.

ChEMBL ID
CHEMBL58547
Modality
Protein / peptide
Highest clinical stage
Phase 2
Record name
IPAMORELIN
Synonyms, codes and trade names
Synonyms and development codes
Ipamorelin · NNC 26-0161 · NNC-26-0161 · NNC-260161

Identity check: Identical standard InChIKey to the PubChem record. Source: ChEMBL CHEMBL58547 (EMBL-EBI, CC BY-SA 3.0) · retrieved 2026-10-07

Registered clinical trials

Studies registered on ClinicalTrials.gov that list Ipamorelin as an intervention. Studies that only measure the molecule as a biomarker, or use it only as a comparator or background arm for another drug, are excluded. A registration describes a planned or completed protocol; it does not report a result. Active studies are listed first.

2 registered studies matched.

By highest phase
Phase 2 · 2
By registry status
Completed · 2
StudyPhase · statusConditionsSponsor · size
Safety and Efficacy of Ipamorelin Compared to Placebo for the Recovery of Gastrointestinal FunctionNCT01280344 · start 2011-04 · primary completion 2013-06Phase 2CompletedGastrointestinal DysmotilityHelsinn Therapeutics (U.S.), Inc320 participants
Safety and Efficacy of Ipamorelin for Management of Post-Operative IleusNCT00672074 · start 2008-04 · primary completion 2009-12Phase 2CompletedIleusHelsinn Therapeutics (U.S.), Inc117 participants

Registry check 2026-10-09 · Run this search on ClinicalTrials.gov

Human intervention studies

Selected studies in which participants received Ipamorelin, with their indexed or reviewed study type. Check the original article for the formulation, population and controls. Studies that only measured the molecule, or used it as a comparator, are listed separately below and are not counted as intervention studies.

  1. Human study · PubMed trial index Compound given to participants

    Prospective, randomized, controlled, proof-of-concept study of the Ghrelin mimetic ipamorelin for the management of postoperative ileus in bowel resection patients.

    Beck DE, Sweeney WB, McCarter MD et al. · International journal of colorectal disease · 2014

    PMID 25331030 · DOI: 10.1007/s00384-014-2030-8 · Registration NCT00672074

  2. Human study · PubMed trial index Compound given to participants

    Pharmacokinetic-pharmacodynamic modeling of ipamorelin, a growth hormone releasing peptide, in human volunteers.

    Gobburu JV, Agersø H, Jusko WJ et al. · Pharmaceutical research · 1999

    PMID 10496658 · DOI: 10.1023/a:1018955126402

Preclinical research, reviews & other publications

Animal studies, laboratory experiments, reviews and other indexed papers answer different questions. A review is secondary evidence; a case report does not estimate how often an outcome occurs.

  1. Preclinical / laboratory research

    Ipamorelin, the first selective growth hormone secretagogue.

    Raun K, Hansen BS, Johansen NL et al. · European journal of endocrinology · 1998

    PMID 9849822 · DOI: 10.1530/eje.0.1390552

Ipamorelin supplier sources

Scientific sources describe molecules and experiments. The commercial links below identify recorded supplier packages. A publication or chemical database entry does not verify the seller, purity, sterility or contents of a lot. Some links are affiliate links; see our disclosure.

Ipamorelin for sale: compare prices, sizes and forms from every tracked supplier →

SupplierRecorded packagesExample source listing
American PeptidesUSD5mg Vial · 10mg Vial2 recorded offers5mg Vial · $40.00Recorded out of stock · Checked Nov 6, 2026Supplier listing, Ipamorelin 5mg Vial, American Peptides, opens in a new tab
Blank PeptidesUSD10mg Vial1 recorded offers10mg Vial · $55.00Stale observation · Checked Sep 30, 2026Supplier listing, Ipamorelin 10mg Vial, Blank Peptides, opens in a new tab
Amino ClubUSD10mg Vial1 recorded offers10mg Vial · $49.99Stale observation · Checked Oct 14, 2026Supplier listing, Ipamorelin 10mg Vial, Amino Club, opens in a new tab
Amino USAUSD10mg Vial · 5mg Vial2 recorded offers10mg Vial · $50.00Checked Nov 6, 2026Supplier listing, Ipamorelin 10mg Vial, Amino USA, opens in a new tab
Cenexa LabsUSD5mg Vial · 10mg Vial2 recorded offers5mg Vial · $43.99Checked Nov 6, 2026Supplier listing, Ipamorelin 5mg Vial, Cenexa Labs, opens in a new tab
LA PeptidesUSD10mg Vial1 recorded offers10mg Vial · $49.99Checked Nov 3, 2026Supplier listing, Ipamorelin 10mg Vial, LA Peptides, opens in a new tab

Reference sources & further reading

The citations above link directly to publication records. Encyclopedia links are background reading and are not used to establish clinical effectiveness.

Search for additional research

These links run searches; their results have not been individually reviewed and can include unrelated compounds.

Research information is not a dosing guide or a recommendation for personal use. Study findings are specific to the formulation, population and methods tested. Read our source and correction policy.

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