Home / Research library / Phenibut FAA Powder
Phenibut FAA Powder: molecular data, studies & sources
Phenibut is a non-peptide compound with literature covering clinical use, intoxication and dependence. A 2020 systematic review combined clinical-trial safety information and case reports. A 2025 study of a named phenibut capsule preparation was observational, without a randomized placebo comparison. Neither publication establishes the safety of unsupervised use or equivalence of supplier powders.
Overview sources: PMID 32340063 · PMID 40807194
Compiled by PeptideTech Editors · Sources checked · Selected bibliography, not a systematic review
Molecular formula, weight & structure
- Molecular formula (MF)
- C10H13NO2
- Molecular weight (MW)
- 179.22 g/mol
- PubChem compound ID
- 14113
- Record title
- Phenibut
The free amino acid (FAA) has a different formula and molecular weight from phenibut hydrochloride. Phenibut studies do not automatically establish equivalence between a studied preparation and a supplier powder.
Source: PubChem CID 14113 · retrieved 2026-09-21 · Identity cross-reference

Chemical identifiers and source data
- IUPAC name
- 4-amino-3-phenylbutanoic acid
- InChIKey
- DAFOCGYVTAOKAJ-UHFFFAOYSA-N
- SMILES
- C1=CC=C(C=C1)C(CC(=O)O)CN
Identifiers
- PubChem CID
- 14113
- CAS Registry Number
- 1078-21-3via ChemIDplus, EPA DSSTox, FDA GSRS
- FDA UNII
- T2M58D6LA8
- ChEMBL ID
- CHEMBL315818
- InChIKey
- DAFOCGYVTAOKAJ-UHFFFAOYSA-N
CAS numbers are published only from ChemIDplus, EPA DSSTox or the FDA Global Substance Registration System; UNII codes are confirmed in FDA GSRS by structure, sequence or exact name. Checked 2026-10-07.
Calculated molecular descriptors
| Monoisotopic (exact) mass | 179.0946 Da |
|---|---|
| Heavy atoms | 13 |
| Hydrogen-bond donors | 2 |
| Hydrogen-bond acceptors | 2 |
| Rotatable bonds | 4 |
| Topological polar surface area | 63.3 Ų |
| Calculated logP (Crippen) | 1.20 |
| Rings | 1 |
| Stereocenters | 1 |
| Formal charge | 0 |
Computed with RDKit from the published SMILES (Crippen logP, topological polar surface area). Calculated descriptors are not measured properties of a supplied batch.
US regulatory status & drug development
Drug development record (ChEMBL)
Harmonized drug-development record from ChEMBL. The highest clinical stage is the furthest stage reached, as recorded by ChEMBL; it can lag regulatory approvals, and it is not an approval of a research-supplier product.
- ChEMBL ID
- CHEMBL315818
- Modality
- Small molecule
- Highest clinical stage
- Not reported
- Record name
- PHENIBUT
Identity check: Identical standard InChIKey to the PubChem record. Source: ChEMBL CHEMBL315818 (EMBL-EBI, CC BY-SA 3.0) · retrieved 2026-10-07
Registered clinical trials
Studies registered on ClinicalTrials.gov that list Phenibut as an intervention. Studies that only measure the molecule as a biomarker, or use it only as a comparator or background arm for another drug, are excluded. A registration describes a planned or completed protocol; it does not report a result. Active studies are listed first.
No registered study naming this compound was matched. This is a documented gap in registry coverage, not proof that no study exists.
Registry check 2026-10-01 · Run this search on ClinicalTrials.gov
Human intervention studies
Selected studies in which participants received Phenibut, with their indexed or reviewed study type. Check the original article for the formulation, population and controls. Studies that only measured the molecule, or used it as a comparator, are listed separately below and are not counted as intervention studies.
- Human observational study Compound given to participants
Efficacy of Noofen 250 mg Capsules for the Management of Anxious-Neurotic Symptoms in Patients with Adjustment Disorder.
Tērauds E, Dansone G, Troshina Y et al. · Journal of clinical medicine · 2025
Non-interventional observational study of a named capsule preparation in 90 patients. No randomized placebo group; not evidence of equivalence to FAA or HCl supplier powders.
PMID 40807194 · DOI: 10.3390/jcm14155570
- Human study · PubMed trial index Compound given to participants
[Bioequivalence of anvifen and phenibut].
Zhezlova AV, Belolipetskaia VG, Blagodatskikh SV et al. · Eksperimental'naia i klinicheskaia farmakologiia · 2011
PMID 21809698
- Human study · PubMed trial index Compound given to participants
[Effect of phenibut, obsidan and their combination on the human functional state in hyperthermia].
Makarov VI, Tiurenkov IN, Klauchek SV et al. · Fiziologiia cheloveka · 1998
PMID 9567480
Preclinical research, reviews & other publications
Animal studies, laboratory experiments, reviews and other indexed papers answer different questions. A review is secondary evidence; a case report does not estimate how often an outcome occurs.
- Review · secondary evidence
Safety and Tolerability of the Anxiolytic and Nootropic Drug Phenibut: A Systematic Review of Clinical Trials and Case Reports.
Kupats E, Vrublevska J, Zvejniece B et al. · Pharmacopsychiatry · 2020
Systematic review of clinical-trial safety reports and dependence/intoxication case reports. A review is secondary evidence and includes heterogeneous exposures.
PMID 32340063 · DOI: 10.1055/a-1151-5017
- Review · secondary evidence
Phenibut: A drug with one too many "buts".
Gurley BJ, Koturbash I · Basic & clinical pharmacology & toxicology · 2024
PMID 39197876 · DOI: 10.1111/bcpt.14075
Phenibut FAA Powder supplier sources
Scientific sources describe molecules and experiments. The commercial links below identify recorded supplier packages. A publication or chemical database entry does not verify the seller, purity, sterility or contents of a lot. Some links are affiliate links; see our disclosure.
Phenibut FAA Powder for sale: compare prices, sizes and forms from every tracked supplier →
| Supplier | Recorded packages | Example source listing |
|---|---|---|
| Amino USAUSD | 10000mg Powder · 40000mg Powder2 recorded offers | 10000mg Powder · $25.00Checked Nov 6, 2026Supplier listing, Phenibut FAA Powder 10000mg Powder, Amino USA, opens in a new tab |
Reference sources & further reading
- PubChem compound record 14113 — chemical identity and structure.
- ChEMBL drug record CHEMBL315818 — development stage, mechanism and synonyms.
- FDA Global Substance Registration System: UNII T2M58D6LA8 — substance identity, names and codes.
- Wikipedia: Phenibut — Background encyclopedia; not a primary clinical source.
- Grokipedia: Phenibut — Background encyclopedia; not a primary clinical source.
The citations above link directly to publication records. Encyclopedia links are background reading and are not used to establish clinical effectiveness.
Search for additional research
These links run searches; their results have not been individually reviewed and can include unrelated compounds.
Research information is not a dosing guide or a recommendation for personal use. Study findings are specific to the formulation, population and methods tested. Read our source and correction policy.
Related research profiles
Phenibut HCl Powder
C10H14ClNO2
215.67 g/mol · PubChem CID 11499499
5 selected publications · 3 human intervention studies