Tesofensine Capsules: molecular data, studies & sources

Tesofensine Capsules is catalogued here as a research compound. This profile brings together the molecular source record, selected indexed publications and available supplier comparisons. Evidence for a named substance does not authenticate a commercial product.

Compiled by PeptideTech Editors · Sources checked 2026-09-21 · Selected bibliography, not a systematic review

Molecular formula, weight & structure

Molecular formula (MF): C17H23Cl2NO
Molecular weight (MW): 328.3 g/mol
PubChem compound ID: 11370864
Record title: Tesofensine

Values describe the selected PubChem molecular entity. Counterions, salt forms, hydration and sequence changes can alter the supplied material. Confirm the exact identity against the supplier specification.

Source: PubChem CID 11370864 · retrieved 2026-09-21

PubChem 2D molecular structure for Tesofensine Capsules, CID 11370864 — 2D depiction from PubChem. Open to inspect the full image. This drawing represents the selected record, not a vendor batch test.

Chemical identifiers and source data

IUPAC name: (1R,2R,3S,5S)-3-(3,4-dichlorophenyl)-2-(ethoxymethyl)-8-methyl-8-azabicyclo[3.2.1]octane
InChIKey: VCVWXKKWDOJNIT-ZOMKSWQUSA-N
SMILES: CCOC[C@H]1[C@H]2CC[C@H](N2C)C[C@@H]1C3=CC(=C(C=C3)Cl)Cl

Machine-readable PubChem source

Human and clinical studies

Selected human-study records are shown with their indexed or reviewed study type. Check the original article for the intervention, formulation and controls; the molecule can also be a comparator or measured variable.

Human study · PubMed trial index
Subjective and objective effects of the novel triple reuptake inhibitor tesofensine in recreational stimulant users.
Schoedel KA, Meier D, Chakraborty B et al. · Clinical pharmacology and therapeutics · 2010
PMID 20520602 · DOI: 10.1038/clpt.2010.67
Human study · PubMed trial index
Effect of tesofensine on bodyweight loss, body composition, and quality of life in obese patients: a randomised, double-blind, placebo-controlled trial.
Astrup A, Madsbad S, Breum L et al. · Lancet (London, England) · 2008
PMID 18950853 · DOI: 10.1016/S0140-6736(08)61525-1
Human study · PubMed trial index
[The effect of tesofensine on body weight and body composition in obese subjects--secondary publication].
Nielsen AL, Larsen TM, Madsbad S et al. · Ugeskrift for laeger · 2009
PMID 19824222
Human study · PubMed trial index
Tesofensine (NS 2330), a monoamine reuptake inhibitor, in patients with advanced Parkinson disease and motor fluctuations: the ADVANS Study.
Rascol O, Poewe W, Lees A et al. · Archives of neurology · 2008
PMID 18474731 · DOI: 10.1001/archneur.65.5.577
Human study · PubMed trial index
A quantitative enterohepatic circulation model: development and evaluation with tesofensine and meloxicam.
Lehr T, Staab A, Tillmann C et al. · Clinical pharmacokinetics · 2009
PMID 19705923 · DOI: 10.2165/11313370-000000000-00000

Preclinical research, reviews & other publications

Animal studies, laboratory experiments, reviews and other indexed papers answer different questions. A review is secondary evidence; a case report does not estimate how often an outcome occurs.

Review · secondary evidence
Tesofensine, a monoamine reuptake inhibitor for the treatment of obesity.
Bello NT, Zahner MR · Current opinion in investigational drugs (London, England : 2000) · 2009
PMID 19777399
Preclinical / laboratory research
Tesofensine, a novel antiobesity drug, silences GABAergic hypothalamic neurons.
Perez CI, Luis-Islas J, Lopez A et al. · PloS one · 2024
PMID 38656972 · DOI: 10.1371/journal.pone.0300544

Tesofensine Capsules supplier sources

Scientific sources describe molecules and experiments. The commercial links below identify recorded supplier packages. A publication or chemical database entry does not verify the seller, purity, sterility or contents of a lot. Some links are affiliate links; see our disclosure.

Compare all Tesofensine Capsules sizes, forms and supplier prices →

Supplier	Recorded packages	Example source listing
Amino USAUSD	500mcg×30 Capsules1 recorded offers	500mcg×30 Capsules · $112.49Checked Sep 16, 2026Supplier listing
Cenexa LabsUSD	500mcg×60 Capsules1 recorded offers	500mcg×60 Capsules · $136.99Checked Sep 16, 2026Supplier listing

Reference sources & further reading

PubChem compound record 11370864 — chemical identity and structure.
Wikipedia: Tesofensine — Background encyclopedia; not a primary clinical source.

The citations above link directly to publication records. Encyclopedia links are background reading and are not used to establish clinical effectiveness.

Search for additional research

These links run searches; their results have not been individually reviewed and can include unrelated compounds.

Research information is not a dosing guide or a recommendation for personal use. Study findings are specific to the formulation, population and methods tested. Read our source and correction policy.