Triptorelin: molecular data, studies & sources

Molecular formula, weight & structure

Molecular formula (MF)

C64H82N18O13

Molecular weight (MW)

1311.4 g/mol

PubChem compound ID

25074470

Record title

Triptorelin

Values describe the selected PubChem molecular entity. Counterions, salt forms, hydration and sequence changes can alter the supplied material. Confirm the exact identity against the supplier specification.

Source: PubChem CID 25074470 · retrieved 2026-09-21

US regulatory status & drug development

Triptorelin (listed as triptorelin pamoate) is the active ingredient of FDA-approved medicines that Drugs@FDA lists as marketed prescription products (checked October 7, 2026): TRELSTAR (NDA 020715, approved June 15, 2000; NDA 021288, approved June 29, 2001; NDA 022437, approved March 10, 2010) and TRIPTODUR (NDA 208956, approved June 29, 2017). Research-labelled Triptorelin listings are not TRELSTAR or TRIPTODUR and are not FDA-approved drugs.

An FDA approval covers a defined medicine, formulation and labelled use. It does not extend to research-labelled material sold under the same compound name. Identity basis: Same active moiety: the approved products list triptorelin pamoate; the research record is triptorelin (PubChem CID 25074470).

Source: Drugs@FDA via openFDA (application records; DailyMed label set IDs) · checked 2026-10-07. openFDA data are not intended for clinical decisions.

Registered clinical trials

Studies registered on ClinicalTrials.gov that list Triptorelin as an intervention. Studies that only measure the molecule as a biomarker, or use it only as a comparator or background arm for another drug, are excluded. A registration describes a planned or completed protocol; it does not report a result. Active studies are listed first.

29 registered studies matched, 12 currently active or recruiting, 4 with results posted on ClinicalTrials.gov.

By highest phase

Phase 4 · 8Phase 3 · 13Phase 2 · 5Early phase 1 · 1Not applicable · 2

By registry status

Recruiting · 10Completed · 9Unknown · 8Not Yet Recruiting · 2

Registry check 2026-10-09 · Run this search on ClinicalTrials.gov

Human intervention studies

Selected studies in which participants received Triptorelin, with their indexed or reviewed study type. Check the original article for the formulation, population and controls. Studies that only measured the molecule, or used it as a comparator, are listed separately below and are not counted as intervention studies.

1. Human study · PubMed trial index Compound given to participants

   A Phase 3, Open-Label, Single-Arm Trial of the Efficacy and Safety of Triptorelin 6-Month Formulation in Chinese Children with Central Precocious Puberty.

   Yu X, Cheng X, Wei H et al. · Advances in therapy · 2024

   PMID 39412628 · DOI: 10.1007/s12325-024-02991-x · Registration NCT05029622

2. Human study · PubMed trial index Compound given to participants

   Efficacy and safety of triptorelin 6-month formulation in patients with central precocious puberty.

   Klein K, Yang J, Aisenberg J et al. · Journal of pediatric endocrinology & metabolism : JPEM · 2016

   PMID 26887034 · DOI: 10.1515/jpem-2015-0376

Human studies that measured Triptorelin or used it as a comparator

Indexed as human studies in PubMed, but participants were not given Triptorelin as the studied intervention, or the record does not establish that they were. They describe measurements or comparisons, not the effect of administering the compound.

1. Human study · PubMed trial index Comparator arm for another drug

   Comparison of dienogest versus triptorelin acetate in premenopausal women with adenomyosis: a prospective clinical trial.

   Fawzy M, Mesbah Y · Archives of gynecology and obstetrics · 2015

   PMID 25990480 · DOI: 10.1007/s00404-015-3755-5

Preclinical research, reviews & other publications

Animal studies, laboratory experiments, reviews and other indexed papers answer different questions. A review is secondary evidence; a case report does not estimate how often an outcome occurs.

1. Research publication · design requires review

   Cost-Effectiveness Analysis of Triptorelin, Goserelin, and Leuprolide in the Treatment of Patients With Metastatic Prostate Cancer: A Societal Perspective.

   Rezaee M, Karimzadeh I, Hashemi-Meshkini A et al. · Value in health regional issues · 2024

   PMID 38663058 · DOI: 10.1016/j.vhri.2024.01.004

2. Review · secondary evidence

   Unveiling the Effects of Triptorelin on Endocrine Profiles: Insights From Healthy, Polycystic Ovary Syndrome, and Hypothalamic Amenorrhea Women.

   Kumari R, Muneshwar KN, Pathade AG et al. · Cureus · 2023

   PMID 37809244 · DOI: 10.7759/cureus.44752

3. Review · secondary evidence

   Triptorelin for the treatment of endometriosis.

   Leone Roberti Maggiore U, Scala C, Remorgida V et al. · Expert opinion on pharmacotherapy · 2014

   PMID 24832495 · DOI: 10.1517/14656566.2014.916279

Triptorelin supplier sources

Scientific sources describe molecules and experiments. The commercial links below identify recorded supplier packages. A publication or chemical database entry does not verify the seller, purity, sterility or contents of a lot. Some links are affiliate links; see our disclosure.

Triptorelin for sale: compare prices, sizes and forms from every tracked supplier →

Reference sources & further reading

• PubChem compound record 25074470 — chemical identity and structure.
• ChEMBL drug record CHEMBL1201334 — development stage, mechanism and synonyms.
• FDA Global Substance Registration System: UNII 9081Y98W2V — substance identity, names and codes.
• Drugs@FDA: NDA 020715 — US approval record for a medicine with the same active ingredient.
• Drugs@FDA: NDA 021288 — US approval record for a medicine with the same active ingredient.
• Drugs@FDA: NDA 022437 — US approval record for a medicine with the same active ingredient.
• Drugs@FDA: NDA 208956 — US approval record for a medicine with the same active ingredient.
• Wikipedia: Triptorelin — Background encyclopedia; not a primary clinical source.

The citations above link directly to publication records. Encyclopedia links are background reading and are not used to establish clinical effectiveness.

Research information is not a dosing guide or a recommendation for personal use. Study findings are specific to the formulation, population and methods tested. Read our source and correction policy.

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