MK-677 vs Sermorelin: prices, identity and regulatory status (2026)
MK-677 and Sermorelin are different research compounds, not substitutes for each other: MK-677 is a single compound (C27H36N4O5S); Sermorelin is a 29-amino-acid peptide (C149H246N44O42S). Lowest current in-stock prices: MK-677 15mg×60 from $129.99 at Cenexa Labs; Sermorelin 5mg from $49.99 ($10.00/mg) at Nova Peptide Supply. MK-677 has no Drugs@FDA application; Sermorelin was FDA-approved but every application is discontinued.
Research use only. These are research-use-only listings sold for laboratory research, not prescription medicines and not for human use. PeptideTech does not compare effects or provide dosing information.
MK-677 vs Sermorelin: current prices and packages
| Compared property | MK-677 | Sermorelin |
|---|---|---|
| Category | SARMs | Growth hormone |
| Compared package | 15mg×60 · Capsules | 5mg · Vial |
| Lowest current price | $129.99 at Cenexa Labs, checked Oct 16, 2026 | $49.99 at Nova Peptide Supply, checked Oct 16, 2026 |
| Price per labelled mg | Exact package total only | $10.00/mg |
| Package sizes | 25mg-per-mL-30mL, 10mg×60, 12.5mg×60, 15mg×60, 25mg×60, 2000mg | 2mg, 5mg, 10mg, 15mg |
| Vendors with current prices | 1 | 3 |
| Form at this package | Capsules | Vial |
| Stock | In stock | In stock |
Prices exclude shipping. The price per labelled mg is always given per mg, so different package sizes compare directly; it is shown only for single-compound vials and powders with a labelled mass. Blends, capsules, liquids and IU-labelled packages are compared by package total.
Identity, regulatory status and registered research
| Compared property | MK-677 | Sermorelin |
|---|---|---|
| Molecular formula | C27H36N4O5S | C149H246N44O42S |
| Molecular weight | 528.7 g/mol | 3357.9 g/mol |
| Sequence | — | H-Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH2 (29 residues) |
| CAS Registry Number | 159634-47-6 | 86168-78-7 |
| Registered clinical trials | 4 · Phase 2: 3, Not applicable: 1 | None recorded |
| Human intervention studies | 4 | 2 |
| US regulatory status | No Drugs@FDA application (checked October 7, 2026) · Drugs@FDA search | FDA-approved as Geref, all applications discontinued (NDA 019863 and NDA 020443; checked October 7, 2026)DiscontinuedGEREF · NDA 019863 · 1990GEREF · NDA 020443 · 1997Research listings are not these medicines. |
Identity data: PubChem, FDA GSRS and EPA records; registry counts: ClinicalTrials.gov; status: Drugs@FDA. A matching name does not verify the contents of a supplier's lot.
Key human studies
MK-677
- MK-0677 (ibutamoren mesylate) for the treatment of patients recovering from hip fracture: a multicenter, randomized, placebo-controlled phase IIb study. Archives of gerontology and geriatrics, 2011
- Effects of an oral ghrelin mimetic on body composition and clinical outcomes in healthy older adults: a randomized trial. Annals of internal medicine, 2008
- Growth hormone secretagogue MK-677: no clinical effect on AD progression in a randomized trial. Neurology, 2008
Sermorelin
- Once daily subcutaneous growth hormone-releasing hormone therapy accelerates growth in growth hormone-deficient children during the first year of therapy. Geref International Study Group. The Journal of clinical endocrinology and metabolism, 1996
- A comparative study of growth hormone (GH) and GH-releasing hormone(1-29)-NH2 for stimulation of growth in children with GH deficiency. Acta paediatrica (Oslo, Norway : 1992). Supplement, 1993
Studies are listed as records, newest first; they are not evidence that a research product is safe or effective.
Research-use listings for each compound
Research-use-only listings sold for laboratory research, not prescription medicines and not for human use.
MK-677
MK-677 is a catalogue entry whose compound-specific reference review has not yet been completed.
$129.99 · 15mg×60 · Cenexa Labs
View at Cenexa Labs, MK-677 15mg×60, opens in a new tabPeptideTech does not sell or fulfill products. Some outgoing links can earn a commission, which does not determine price order. How we rankMK-677 prices →Price history →Sermorelin
Sermorelin is a catalogue entry whose compound-specific reference review has not yet been completed.
$49.99 · 5mg · $10.00/mg · Nova Peptide Supply
View at Nova Peptide Supply, Sermorelin 5mg, opens in a new tabPeptideTech does not sell or fulfill products. Some outgoing links can earn a commission, which does not determine price order. How we rankSermorelin prices →Price history →Related comparisons
Questions
Automated price sources are scheduled daily; other sources are checked manually. Check the offer's last successful source timestamp. A code is shown when it is attached to an offer or affiliate link. The displayed price includes a discount only when that code is cart-verified and the discounted price is explicitly recorded; otherwise it is the vendor's listed price. Prices exclude shipping. Stock status is captured at the same time. Rankings are by displayed price only. PeptideTech earns a commission when you buy through a link; it never changes the order.
Full method →