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Other compounds

MK-677: molecular data, studies & sources

MK-677 is catalogued here as a research compound. This profile brings together the molecular source record, selected indexed publications and available supplier comparisons. Evidence for a named substance does not authenticate a commercial product.

Compiled by PeptideTech Editors · Sources checked · Selected bibliography, not a systematic review

Molecular formula, weight & structure

Molecular formula (MF)
C27H36N4O5S
Molecular weight (MW)
528.7 g/mol
PubChem compound ID
178024
Record title
Ibutamoren

Values describe the selected PubChem molecular entity. Counterions, salt forms, hydration and sequence changes can alter the supplied material. Confirm the exact identity against the supplier specification.

Source: PubChem CID 178024 · retrieved 2026-09-21

PubChem 2D molecular structure for MK-677, CID 178024
2D depiction from PubChem. Open to inspect the full image. This drawing represents the selected record, not a vendor batch test.
Chemical identifiers and source data
IUPAC name
2-amino-2-methyl-N-[(2R)-1-(1-methylsulfonylspiro[2H-indole-3,4'-piperidine]-1'-yl)-1-oxo-3-phenylmethoxypropan-2-yl]propanamide
InChIKey
UMUPQWIGCOZEOY-JOCHJYFZSA-N
SMILES
CC(C)(C(=O)N[C@H](COCC1=CC=CC=C1)C(=O)N2CCC3(CC2)CN(C4=CC=CC=C34)S(=O)(=O)C)N
Machine-readable PubChem source

Human and clinical studies

Selected human-study records are shown with their indexed or reviewed study type. Check the original article for the intervention, formulation and controls; the molecule can also be a comparator or measured variable.

  1. Human study · PubMed trial index

    Effects of oral administration of ibutamoren mesylate, a nonpeptide growth hormone secretagogue, on the growth hormone-insulin-like growth factor I axis in growth hormone-deficient children.

    Codner E, Cassorla F, Tiulpakov AN et al. · Clinical pharmacology and therapeutics · 2001

    PMID 11452249 · DOI: 10.1067/mcp.2001.116514

  2. Human study · PubMed trial index

    MK-0677 (ibutamoren mesylate) for the treatment of patients recovering from hip fracture: a multicenter, randomized, placebo-controlled phase IIb study.

    Adunsky A, Chandler J, Heyden N et al. · Archives of gerontology and geriatrics · 2011

    PMID 21067829 · DOI: 10.1016/j.archger.2010.10.004

Preclinical research, reviews & other publications

Animal studies, laboratory experiments, reviews and other indexed papers answer different questions. A review is secondary evidence; a case report does not estimate how often an outcome occurs.

No additional matching publication was retained. The search links below allow further investigation; they are not evidence that a study exists.

    MK-677 supplier sources

    Scientific sources describe molecules and experiments. The commercial links below identify recorded supplier packages. A publication or chemical database entry does not verify the seller, purity, sterility or contents of a lot. Some links are affiliate links; see our disclosure.

    Compare all MK-677 sizes, forms and supplier prices →

    SupplierRecorded packagesExample source listing
    Cenexa LabsUSD15mg×60 Capsules1 recorded offers15mg×60 Capsules · $129.99Checked Sep 16, 2026Supplier listing
    Amino USAUSD25mg-per-mL-30mL Solution1 recorded offers25mg-per-mL-30mL Solution · $45.00Checked Sep 16, 2026Supplier listing

    Reference sources & further reading

    The citations above link directly to publication records. Encyclopedia links are background reading and are not used to establish clinical effectiveness.

    Search for additional research

    These links run searches; their results have not been individually reviewed and can include unrelated compounds.

    Research information is not a dosing guide or a recommendation for personal use. Study findings are specific to the formulation, population and methods tested. Read our source and correction policy.