Skip to content
PeptideTech
Cart

Home / Research library / Acetyl Hexapeptide-3 (Argireline)

Peptides

Acetyl Hexapeptide-3 (Argireline): molecular data, studies & sources

Acetyl Hexapeptide-3 (Argireline) is catalogued here as a research compound. This profile brings together the molecular source record, selected indexed publications and available supplier comparisons. Evidence for a named substance does not authenticate a commercial product.

Compiled by PeptideTech Editors · Sources checked · Selected bibliography, not a systematic review

Molecular formula, weight & structure

Molecular formula (MF)
C35H62N14O11S
Molecular weight (MW)
887.0 g/mol
PubChem compound ID
71587772
Record title
Acetyl hexapeptide-3

Values describe the selected PubChem molecular entity. Counterions, salt forms, hydration and sequence changes can alter the supplied material. Confirm the exact identity against the supplier specification.

Source: PubChem CID 71587772 · retrieved 2026-09-21

PubChem 2D molecular structure for Acetyl Hexapeptide-3 (Argireline), CID 71587772
2D depiction from PubChem. Open to inspect the full image. This drawing represents the selected record, not a vendor batch test.
Chemical identifiers and source data
IUPAC name
(4S)-4-acetamido-5-[[(2S)-1-[[(2S)-1-[[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]hex-5-enoic acid
InChIKey
AJLNZWYOJAWBCR-OOPVGHQCSA-N
SMILES
CC(=O)N[C@@H](CCC(=O)O)C(=C)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N
Machine-readable PubChem source

Human and clinical studies

Selected human-study records are shown with their indexed or reviewed study type. Check the original article for the intervention, formulation and controls; the molecule can also be a comparator or measured variable.

  1. Human study · PubMed trial index

    Pilot study of topical acetyl hexapeptide-8 in the treatment for blepharospasm in patients receiving botulinum toxin therapy.

    Lungu C, Considine E, Zahir S et al. · European journal of neurology · 2013

    PMID 23146065 · DOI: 10.1111/ene.12009

Preclinical research, reviews & other publications

Animal studies, laboratory experiments, reviews and other indexed papers answer different questions. A review is secondary evidence; a case report does not estimate how often an outcome occurs.

  1. Review · secondary evidence

    Acetyl Hexapeptide-8 in Cosmeceuticals-A Review of Skin Permeability and Efficacy.

    Zdrada-Nowak J, Surgiel-Gemza A, Szatkowska M et al. · International journal of molecular sciences · 2025

    PMID 40565185 · DOI: 10.3390/ijms26125722

  2. Research publication · design requires review

    Public Interest in Acetyl Hexapeptide-8: Longitudinal Analysis.

    Olsson SE, Sreepad B, Lee T et al. · JMIR dermatology · 2024

    PMID 38376906 · DOI: 10.2196/54217

  3. Research publication · design requires review

    Safety Assessment of Acetyl Hexapeptide-8 Amide as Used in Cosmetics.

    Johnson W, Bergfeld WF, Belsito DV et al. · International journal of toxicology · 2025

    PMID 40673537 · DOI: 10.1177/10915818251340391

  4. Research publication · design requires review

    Polydioxanone Bioactive Sutures-Acetyl Hexapeptide-8 (Argireline): An Intelligent System for Controlled Release in Facial Harmonization.

    Velazco de Maldonado GJ, Suárez-Vega DV, Miller-Kobisher B et al. · Journal of cutaneous and aesthetic surgery · 2023

    PMID 38314369 · DOI: 10.4103/JCAS.JCAS_34_23

  5. Preclinical / laboratory research

    Topical delivery of acetyl hexapeptide-8 from different emulsions: influence of emulsion composition and internal structure.

    Hoppel M, Reznicek G, Kählig H et al. · European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences · 2015

    PMID 25497319 · DOI: 10.1016/j.ejps.2014.12.006

Acetyl Hexapeptide-3 (Argireline) supplier sources

Scientific sources describe molecules and experiments. The commercial links below identify recorded supplier packages. A publication or chemical database entry does not verify the seller, purity, sterility or contents of a lot. Some links are affiliate links; see our disclosure.

Compare all Acetyl Hexapeptide-3 (Argireline) sizes, forms and supplier prices →

SupplierRecorded packagesExample source listing
Cenexa LabsUSD200mg Powder1 recorded offers200mg Powder · $209.99Checked Sep 16, 2026Supplier listing

Reference sources & further reading

The citations above link directly to publication records. Encyclopedia links are background reading and are not used to establish clinical effectiveness.

Search for additional research

These links run searches; their results have not been individually reviewed and can include unrelated compounds.

Research information is not a dosing guide or a recommendation for personal use. Study findings are specific to the formulation, population and methods tested. Read our source and correction policy.

Related research profiles