Home / Research library / BPC-157
BPC-157: molecular data, studies & sources
BPC-157 is a synthetic pentadecapeptide. Much of its published research concerns laboratory and animal models. A human pilot report is included below, but a small pilot study is not a substitute for a large controlled trial and cannot establish general clinical effectiveness or safety.
Overview sources: PMID 20225319 · PMID 40131143
Compiled by PeptideTech Editors · Sources checked · Selected bibliography, not a systematic review
Molecular formula, weight & structure
- Molecular formula (MF)
- C62H98N16O22
- Molecular weight (MW)
- 1419.5 g/mol
- PubChem compound ID
- 9941957
- Record title
- Bpc-157
Values describe the selected PubChem molecular entity. Counterions, salt forms, hydration and sequence changes can alter the supplied material. Confirm the exact identity against the supplier specification.
Source: PubChem CID 9941957 · retrieved 2026-09-21
Chemical identifiers and source data
- IUPAC name
- (4S)-4-[(2-aminoacetyl)amino]-5-[(2S)-2-[(2S)-2-[(2S)-2-[[2-[[(2S)-6-amino-1-[(2S)-2-[[(2S)-1-[[(2S)-3-carboxy-1-[[(2S)-3-carboxy-1-[[(2S)-1-[[2-[[(2S)-1-[[(1S)-1-carboxy-2-methylpropyl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxohexan-2-yl]amino]-2-oxoethyl]carbamoyl]pyrrolidine-1-carbonyl]pyrrolidine-1-carbonyl]pyrrolidin-1-yl]-5-oxopentanoic acid
- InChIKey
- HEEWEZGQMLZMFE-RKGINYAYSA-N
- SMILES
- C[C@@H](C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@@H]2CCCN2C(=O)[C@@H]3CCCN3C(=O)[C@@H]4CCCN4C(=O)[C@H](CCC(=O)O)NC(=O)CN
Identifiers & sequence
- PubChem CID
- 9941957
- CAS Registry Number
- 137525-51-0via ChemIDplus, EPA DSSTox, FDA GSRS
- FDA UNII
- 8ED8NXK95P
- ChEMBL ID
- CHEMBL4297358
- InChIKey
- HEEWEZGQMLZMFE-RKGINYAYSA-N
- Wikidata
- Q27270252
Other names and development codes: PL-10 · PL-14736 · PLD-116
Peptide sequence · 15 residues (one-letter code; X marks a residue without a one-letter code)
GEPPPGKPADDAGLV
Condensed notation with terminal groups and non-standard residues
H-Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val-OH
Source: PubChem Biologic Line Notation. A reference sequence for the record, not an analysis of a supplied batch.
CAS numbers are published only from ChemIDplus, EPA DSSTox or the FDA Global Substance Registration System; UNII codes are confirmed in FDA GSRS by structure, sequence or exact name. Checked 2026-10-07.
Calculated molecular descriptors
| Monoisotopic (exact) mass | 1418.7042 Da |
|---|---|
| Heavy atoms | 100 |
| Hydrogen-bond donors | 16 |
| Hydrogen-bond acceptors | 20 |
| Rotatable bonds | 39 |
| Topological polar surface area | 573.5 Ų |
| Calculated logP (Crippen) | -6.21 |
| Rings | 4 |
| Stereocenters | 12 |
| Formal charge | 0 |
Computed with RDKit from the published SMILES (Crippen logP, topological polar surface area). Calculated descriptors are not measured properties of a supplied batch.
US regulatory status & drug development
Drugs@FDA lists no NDA, BLA or ANDA with BPC-157 as an active ingredient (names searched: BPC-157, BPC 157, BEPECIN; checked October 7, 2026). Research-labelled BPC-157 listings are not FDA-approved drugs.
An FDA approval covers a defined medicine, formulation and labelled use. It does not extend to research-labelled material sold under the same compound name. Identity basis: No INN; the code name BPC-157 and the synonym Bepecin were searched.
Source: Drugs@FDA via openFDA (active-ingredient search for BPC-157, BPC 157, BEPECIN) · checked . openFDA data are not intended for clinical decisions.
Drug development record (ChEMBL)
Harmonized drug-development record from ChEMBL. The highest clinical stage is the furthest stage reached, as recorded by ChEMBL; it can lag regulatory approvals, and it is not an approval of a research-supplier product.
- ChEMBL ID
- CHEMBL4297358
- Modality
- Protein / peptide
- Highest clinical stage
- Phase 1
- Record name
- BPC-157
Synonyms, codes and trade names
- Synonyms and development codes
- PL-10 · PL-14736 · PLD-116
Identity check: Identical standard InChIKey to the PubChem record. Source: ChEMBL CHEMBL4297358 (EMBL-EBI, CC BY-SA 3.0) · retrieved 2026-10-07
Registered clinical trials
Studies registered on ClinicalTrials.gov that list BPC-157 as an intervention. Studies that only measure the molecule as a biomarker, or use it only as a comparator or background arm for another drug, are excluded. A registration describes a planned or completed protocol; it does not report a result. Active studies are listed first.
3 registered studies matched, 2 currently active or recruiting.
- By highest phase
- Phase 2 · 1Phase 1 · 2
- By registry status
- Not Yet Recruiting · 1Recruiting · 1Unknown · 1
| Study | Phase · status | Conditions | Sponsor · size |
|---|---|---|---|
| Impact of BPC-157 on Recovery Following Rotator Cuff Repair SurgeryNCT07803250 · start 2027-01-01 · primary completion 2027-08-01 | Phase 1Not Yet Recruiting | Rotator Cuff Tear | University of Arkansas30 participants |
| BPC 157 for Acute Hamstring Muscle Strain RepairNCT07437547 · start 2026-02-02 · primary completion 2027-02-14 | Phase 2Recruiting | Hamstring Muscle Strain · Skeletal Muscle Injury | Hudson Biotech120 participants |
| PCO-02 - Safety and Pharmacokinetics TrialNCT02637284 · start 2015-10 · primary completion 2016-02 | Phase 1Unknown | Healthy Volunteers | PharmaCotherapia d.o.o.42 participants |
Registry check 2026-10-09 · Run this search on ClinicalTrials.gov
Human intervention studies
Selected studies in which participants received BPC-157, with their indexed or reviewed study type. Check the original article for the formulation, population and controls. Studies that only measured the molecule, or used it as a comparator, are listed separately below and are not counted as intervention studies.
- Human pilot study Compound given to participants
Safety of Intravenous Infusion of BPC157 in Humans: A Pilot Study.
Lee E, Burgess K · Alternative therapies in health and medicine · 2025
Small human pilot report. Sample size and study design limit safety and efficacy conclusions.
PMID 40131143
Preclinical research, reviews & other publications
Animal studies, laboratory experiments, reviews and other indexed papers answer different questions. A review is secondary evidence; a case report does not estimate how often an outcome occurs.
- Preclinical / laboratory research
Pentadecapeptide BPC 157 (PL 14736) improves ligament healing in the rat.
Cerovecki T, Bojanic I, Brcic L et al. · Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2010
PMID 20225319 · DOI: 10.1002/jor.21107
- Review · secondary evidence
Multifunctionality and Possible Medical Application of the BPC 157 Peptide-Literature and Patent Review.
Józwiak M, Bauer M, Kamysz W et al. · Pharmaceuticals (Basel, Switzerland) · 2025
PMID 40005999 · DOI: 10.3390/ph18020185
- Review · secondary evidence
Regeneration or Risk? A Narrative Review of BPC-157 for Musculoskeletal Healing.
McGuire FP, Martinez R, Lenz A et al. · Current reviews in musculoskeletal medicine · 2025
PMID 40789979 · DOI: 10.1007/s12178-025-09990-7
- Review · secondary evidence
Emerging Use of BPC-157 in Orthopaedic Sports Medicine: A Systematic Review.
Vasireddi N, Hahamyan H, Salata MJ et al. · HSS journal : the musculoskeletal journal of Hospital for Special Surgery · 2025
PMID 40756949 · DOI: 10.1177/15563316251355551
- Review · secondary evidence
Stable Gastric Pentadecapeptide BPC 157 and Wound Healing.
Seiwerth S, Milavic M, Vukojevic J et al. · Frontiers in pharmacology · 2021
PMID 34267654 · DOI: 10.3389/fphar.2021.627533
- Research publication · design requires review
Intra-Articular Injection of BPC 157 for Multiple Types of Knee Pain.
Lee E, Padgett B · Alternative therapies in health and medicine · 2021
PMID 34324435
BPC-157 supplier sources
Scientific sources describe molecules and experiments. The commercial links below identify recorded supplier packages. A publication or chemical database entry does not verify the seller, purity, sterility or contents of a lot. Some links are affiliate links; see our disclosure.
BPC-157 for sale: compare prices, sizes and forms from every tracked supplier →
| Supplier | Recorded packages | Example source listing |
|---|---|---|
| American PeptidesUSD | 5mg Vial · 10mg Vial · 15mg Vial3 recorded offers | 5mg Vial · $60.00Checked Nov 6, 2026Supplier listing, BPC-157 5mg Vial, American Peptides, opens in a new tab |
| Blank PeptidesUSD | 10mg Vial1 recorded offers | 10mg Vial · $55.00Stale observation · Checked Sep 30, 2026Supplier listing, BPC-157 10mg Vial, Blank Peptides, opens in a new tab |
| Amino ClubUSD | 10mg Vial · 15mg Spray2 recorded offers | 10mg Vial · $39.99Stale observation · Checked Oct 14, 2026Supplier listing, BPC-157 10mg Vial, Amino Club, opens in a new tab |
| Nova Peptide SupplyUSD | 10mg Vial · 5mg Vial2 recorded offers | 10mg Vial · $59.99Checked Nov 6, 2026Supplier listing, BPC-157 10mg Vial, Nova Peptide Supply, opens in a new tab |
| Amino USAUSD | 10mg Vial · 15mg Vial · 20mg Vial · 5mg Vial · 500mcg×60 Capsules5 recorded offers | 10mg Vial · $58.00Checked Nov 6, 2026Supplier listing, BPC-157 10mg Vial, Amino USA, opens in a new tab |
| Cenexa LabsUSD | 10mg Vial · 5mg Vial2 recorded offers | 10mg Vial · $74.99Checked Nov 6, 2026Supplier listing, BPC-157 10mg Vial, Cenexa Labs, opens in a new tab |
| LA PeptidesUSD | 500mcg×60 Capsules · 10mg Spray · 10mg Vial3 recorded offers | 500mcg×60 Capsules · $89.99Checked Nov 3, 2026Supplier listing, BPC-157 500mcg×60 Capsules, LA Peptides, opens in a new tab |
Reference sources & further reading
- PubChem compound record 9941957 — chemical identity and structure.
- ChEMBL drug record CHEMBL4297358 — development stage, mechanism and synonyms.
- FDA Global Substance Registration System: UNII 8ED8NXK95P — substance identity, names and codes.
- Wikipedia: BPC-157 — Background encyclopedia; not a primary clinical source.
- Grokipedia: BPC-157 — Background encyclopedia; not a primary clinical source.
The citations above link directly to publication records. Encyclopedia links are background reading and are not used to establish clinical effectiveness.
Search for additional research
These links run searches; their results have not been individually reviewed and can include unrelated compounds.
Research information is not a dosing guide or a recommendation for personal use. Study findings are specific to the formulation, population and methods tested. Read our source and correction policy.
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