Other compounds

Andarine (S4): molecular data, studies & sources

Andarine (S4) is catalogued here as a research compound. This profile brings together the molecular source record, selected indexed publications and available supplier comparisons. Evidence for a named substance does not authenticate a commercial product.

Compiled by PeptideTech Editors · Sources checked 2026-10-09 · Selected bibliography, not a systematic review

Molecular formula, weight & structure

Molecular formula (MF): C19H18F3N3O6
Molecular weight (MW): 441.4 g/mol
PubChem compound ID: 9824562
Record title: Andarine

Values describe the selected PubChem molecular entity. Counterions, salt forms, hydration and sequence changes can alter the supplied material. Confirm the exact identity against the supplier specification.

Source: PubChem CID 9824562 · retrieved 2026-10-09

2D molecular structure for Andarine (S4), PubChem CID 9824562 — 2D depiction from PubChem. Open to inspect the full image. This drawing represents the selected record, not a vendor batch test.

Chemical identifiers and source data

IUPAC name: (2S)-3-(4-acetamidophenoxy)-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide
InChIKey: YVXVTLGIDOACBJ-SFHVURJKSA-N
SMILES: CC(=O)NC1=CC=C(C=C1)OC[C@@](C)(C(=O)NC2=CC(=C(C=C2)[N+](=O)[O-])C(F)(F)F)O

Machine-readable PubChem source

Identifiers

PubChem CID: 9824562
CAS Registry Number: 401900-40-1via ChemIDplus, EPA DSSTox, FDA GSRS
FDA UNII: 7UT2HAH49H
ChEMBL ID: CHEMBL125236
InChIKey: YVXVTLGIDOACBJ-SFHVURJKSA-N
Wikidata: Q4753617

Other names and development codes: GTX-007

CAS numbers are published only from ChemIDplus, EPA DSSTox or the FDA Global Substance Registration System; UNII codes are confirmed in FDA GSRS by structure, sequence or exact name. Checked 2026-10-09.

Calculated molecular descriptors

Monoisotopic (exact) mass	441.1148 Da
Heavy atoms	31
Hydrogen-bond donors	3
Hydrogen-bond acceptors	6
Rotatable bonds	7
Topological polar surface area	130.8 Å²
Calculated logP (Crippen)	3.34
Rings	2
Stereocenters	1
Formal charge	0

Computed with RDKit from the published SMILES (Crippen logP, topological polar surface area). Calculated descriptors are not measured properties of a supplied batch.

Registered clinical trials

Studies registered on ClinicalTrials.gov that list Andarine as an intervention. Studies that only measure the molecule as a biomarker, or use it only as a comparator or background arm for another drug, are excluded. A registration describes a planned or completed protocol; it does not report a result. Active studies are listed first.

No registered study naming this compound was matched. This is a documented gap in registry coverage, not proof that no study exists.

Registry check 2026-10-01 · Run this search on ClinicalTrials.gov

Human intervention studies

Selected studies in which participants received Andarine, with their indexed or reviewed study type. Check the original article for the formulation, population and controls. Studies that only measured the molecule, or used it as a comparator, are listed separately below and are not counted as intervention studies.

No human study that administered this compound was retained in this selected bibliography. This is a documented evidence gap in our selection, not proof that no study exists.

Preclinical research, reviews & other publications

Animal studies, laboratory experiments, reviews and other indexed papers answer different questions. A review is secondary evidence; a case report does not estimate how often an outcome occurs.

Research publication · design requires review
In vitro anti-carcinogenic effect of andarine as a selective androgen receptor modulator on MIA-PaCa-2 cells by decreased proliferation and cell-cycle arrest at G0/G1 phase.
Bölük A, Yavuz M, Takanlou MS et al. · Biochemical and biophysical research communications · 2023
PMID 37302286 · DOI: 10.1016/j.bbrc.2023.06.016
Preclinical / laboratory research
Detection of the selective androgen receptor modulator andarine (S-4) in a routine equine blood doping control sample.
Cawley AT, Smart C, Greer C et al. · Drug testing and analysis · 2015
PMID 26456227 · DOI: 10.1002/dta.1867
Research publication · design requires review
Detection of the selective androgen receptor modulator S-4 (Andarine) in a doping control sample.
Starcevic B, Ahrens BD, Butch AW et al. · Drug testing and analysis · 2013
PMID 23427117 · DOI: 10.1002/dta.1466
Research publication · design requires review
Detection of the arylpropionamide-derived selective androgen receptor modulator (SARM) S-4 (Andarine) in a black-market product.
Thevis M, Geyer H, Kamber M et al. · Drug testing and analysis · 2009
PMID 20355219 · DOI: 10.1002/dta.91
Research publication · design requires review
Mass spectrometric characterization of urinary metabolites of the selective androgen receptor modulator andarine (S-4) for routine doping control purposes.
Thevis M, Thomas A, Fusshöller G et al. · Rapid communications in mass spectrometry : RCM · 2010
PMID 20623476 · DOI: 10.1002/rcm.4637

Andarine (S4) supplier sources

Scientific sources describe molecules and experiments. The commercial links below identify recorded supplier packages. A publication or chemical database entry does not verify the seller, purity, sterility or contents of a lot. Some links are affiliate links; see our disclosure.

No priced supplier offers are currently available in this catalog view. The research record remains available independently of stock.

Reference sources & further reading

PubChem compound record 9824562 — chemical identity and structure.
FDA Global Substance Registration System: UNII 7UT2HAH49H — substance identity, names and codes.

The citations above link directly to publication records. Encyclopedia links are background reading and are not used to establish clinical effectiveness.

Search for additional research

These links run searches; their results have not been individually reviewed and can include unrelated compounds.

Research information is not a dosing guide or a recommendation for personal use. Study findings are specific to the formulation, population and methods tested. Read our source and correction policy.