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Eloralintide: molecular data, studies & sources
Eloralintide is catalogued here as a research compound. This profile brings together the molecular source record, selected indexed publications and available supplier comparisons. Evidence for a named substance does not authenticate a commercial product.
Compiled by PeptideTech Editors · Sources checked · Selected bibliography, not a systematic review
Molecular formula, weight & structure
Molecular record not yet resolved
A sufficiently specific molecular record was not resolved for this name. Formula, molecular weight and structure are withheld until the exact sequence, salt or preparation can be verified.
MF: not assigned · MW: not assigned · Structure: not assigned
Registered clinical trials
Studies registered on ClinicalTrials.gov that list Eloralintide as an intervention. Studies that only measure the molecule as a biomarker, or use it only as a comparator or background arm for another drug, are excluded. A registration describes a planned or completed protocol; it does not report a result. Active studies are listed first.
22 registered studies matched, 15 currently active or recruiting, 1 with results posted on ClinicalTrials.gov.
- By highest phase
- Phase 3 · 5Phase 2 · 5Phase 1 · 12
- By registry status
- Recruiting · 12Completed · 7Active Not Recruiting · 2Not Yet Recruiting · 1
| Study | Phase · status | Conditions | Sponsor · size |
|---|---|---|---|
| A Study of Macupatide (LY3532226) in Participants With Obesity or Overweight Without Type 2 DiabetesNCT07765511 · start 2026-10 · primary completion 2027-06 | Phase 1Not Yet Recruiting | Obesity · Overweight | Eli Lilly and Company60 participants |
| A Study of Eloralintide (LY3841136) in Female Participants With Obesity or OverweightNCT07808060 · start 2026-09-15 · primary completion 2027-06 | Phase 1Recruiting | Obesity · Overweight | Eli Lilly and Company34 participants |
| A Study of Eloralintide (LY3841136) in Healthy ParticipantsNCT07701083 · start 2026-07-20 · primary completion 2026-10 | Phase 1Active Not Recruiting | Healthy Volunteers | Eli Lilly and Company58 participants |
| A Study of Eloralintide (LY3841136) in Participants With Obesity or OverweightNCT07738614 · start 2026-07-31 · primary completion 2026-12 | Phase 1Recruiting | Obesity · Overweight | Eli Lilly and Company56 participants |
| A Study of Eloralintide (LY3841136) in Participants With Overweight or ObesityNCT07665879 · start 2026-06-24 · primary completion 2027-08 | Phase 1Recruiting | Overweight · Obesity | Eli Lilly and Company115 participants |
| A Study to Investigate Weight Management With Macupatide and Eloralintide, Alone or in Combination, in Adult Participants With Obesity or OverweightNCT07589608 · start 2026-05-15 · primary completion 2027-09 | Phase 2Recruiting | Overweight · Obesity | Eli Lilly and Company400 participants |
| A Study of Eloralintide (LY3841136) in Participants With Obesity, or Overweight Without Type 2 DiabetesNCT07321886 · start 2026-02-06 · primary completion 2028-03 | Phase 3Recruiting | Obesity · Overweight | Eli Lilly and Company1980 participants |
| Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or OverweightNCT07353931 · start 2026-02-09 · primary completion 2028-03 | Phase 3Recruiting | Osteoarthritis · Overweight or Obesity | Eli Lilly and Company900 participants |
| A Study of Eloralintide (LY3841136) in Participants With Obstructive Sleep Apnea and Obesity or OverweightNCT07369011 · start 2026-02-10 · primary completion 2028-03 | Phase 3Recruiting | Sleep Apnea, Obstructive · Obesity · Overweight | Eli Lilly and Company800 participants |
| A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly IncretinNCT07392190 · start 2026-02-10 · primary completion 2028-06 | Phase 3Recruiting | Overweight · Obesity | Eli Lilly and Company900 participants |
Show 12 more registered studies
| Study | Phase · status | Conditions | Sponsor · size |
|---|---|---|---|
| A Study of Eloralintide (LY3841136) in Participants With Different Levels of Liver Damage and in Participants With Healthy Livers.NCT07401862 · start 2026-02-10 · primary completion 2027-03 | Phase 1Recruiting | Hepatic Insufficiency | Eli Lilly and Company36 participants |
| A Study of Eloralintide (LY3841136) in Participants With Renal Impairment and in Participants With Normal Renal FunctionNCT07426380 · start 2026-02-24 · primary completion 2026-10 | Phase 1Active Not Recruiting | Kidney Disease · Renal Insufficiency Chronic · Kidney Failure, Chronic · Renal Impairment · Renal Insufficiency · End Stage Kidney Disease | Eli Lilly and Company28 participants |
| A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 DiabetesNCT07282600 · start 2025-12-15 · primary completion 2028-01 | Phase 3Recruiting | Overweight · Obesity | Eli Lilly and Company1035 participants |
| A Study of Macupatide (LY3532226) and Eloralintide (LY3841136), Alone or in Combination, in Adults With Obesity or Overweight and With Type 2 DiabetesNCT07215559 · start 2025-10-16 · primary completion 2027-03 | Phase 2Recruiting | Obesity · Overweight · Diabetes Mellitus, Type 2 | Eli Lilly and Company200 participants |
| A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or OverweightNCT06143956 · start 2023-11-17 · primary completion 2027-09 | Phase 2Recruiting | Obesity · Overweight | Eli Lilly and Company1481 participants |
| A Study of Eloralintide (LY3841136) and Eloralintide With Tirzepatide in Participants With Overweight or ObesityNCT06916065 · start 2025-04-09 · primary completion 2026-01-19 | Phase 1Completed | Overweight · Obesity | Eli Lilly and Company188 participants |
| A Study of Eloralintide (LY3841136) in Chinese Participants With Obesity or OverweightNCT06916091 · start 2025-04-21 · primary completion 2025-09-09 | Phase 1Completed | Obesity · Overweight | Eli Lilly and Company30 participants |
| A Study to Investigate Weight Management With LY3841136 and Tirzepatide (LY3298176), Alone or in Combination, in Adult Participants With Obesity or Overweight With Type 2 DiabetesNCT06603571 · start 2024-09-20 · primary completion 2026-07-01 | Phase 2Completed | Obesity · Overweight | Eli Lilly and Company367 participants |
| A Study of LY3841136 in Japanese Participants With Obesity or OverweightNCT06297616 · start 2024-04-15 · primary completion 2025-11-21 | Phase 1Completed | Obesity · Overweight | Eli Lilly and Company128 participants |
| A Study of LY3841136 in Overweight and Obese ParticipantsNCT06345066 · start 2024-04-03 · primary completion 2025-09-29 | Phase 1Completed | Obesity · Overweight | Eli Lilly and Company96 participants |
| A Study of LY3841136 Compared With Placebo in Adult Participants With Obesity or OverweightNCT06230523 · start 2024-02-05 · primary completion 2025-05-30 | Phase 2CompletedResults posted 2026-06-24 | Obesity · Overweight | Eli Lilly and Company263 participants |
| A Study of LY3841136 in Healthy and Overweight ParticipantsNCT05295940 · start 2022-03-30 · primary completion 2024-01-25 | Phase 1Completed | Obesity · Healthy | Eli Lilly and Company148 participants |
Registry check 2026-10-09 · Run this search on ClinicalTrials.gov
Human intervention studies
Selected studies in which participants received Eloralintide, with their indexed or reviewed study type. Check the original article for the formulation, population and controls. Studies that only measured the molecule, or used it as a comparator, are listed separately below and are not counted as intervention studies.
- Human study · PubMed trial index Compound given to participants
Eloralintide (LY3841136), a novel amylin receptor agonist for the treatment of obesity: From discovery to clinical proof of concept.
Briere DA, Qu H, Lansu K et al. · Molecular metabolism · 2025
PMID 41109426 · DOI: 10.1016/j.molmet.2025.102271 · Registration NCT05295940
- Human study · PubMed trial index Compound given to participants
Eloralintide, a selective amylin receptor agonist for the treatment of obesity: a 48-week phase 2, multicentre, double-blind, randomised, placebo-controlled trial.
Billings LK, Hsia S, Bays H et al. · Lancet (London, England) · 2025
PMID 41207310 · DOI: 10.1016/S0140-6736(25)02155-5 · Registration NCT06230523
- Human study · PubMed trial index Compound given to participants
Eloralintide, a selective, long-acting amylin receptor agonist for treatment of obesity: Phase 1 proof of concept.
Bhattachar S, Tham LS, Tidemann-Miller B et al. · Diabetes, obesity & metabolism · 2026
PMID 41559929 · DOI: 10.1111/dom.70439
Preclinical research, reviews & other publications
Animal studies, laboratory experiments, reviews and other indexed papers answer different questions. A review is secondary evidence; a case report does not estimate how often an outcome occurs.
- Research publication · design requires review
Cardiometabolic Risk Reduction Through Selective Amylin Receptor Agonism: Emerging Cardiovascular Implications of Eloralintide.
Sigalov A, Frishman WH · Cardiology in review · 2026
PMID 42745233 · DOI: 10.1097/CRD.0000000000001468
Eloralintide supplier sources
Scientific sources describe molecules and experiments. The commercial links below identify recorded supplier packages. A publication or chemical database entry does not verify the seller, purity, sterility or contents of a lot. Some links are affiliate links; see our disclosure.
No priced supplier offers are currently available in this catalog view. The research record remains available independently of stock.
Reference sources & further reading
The citations above link directly to publication records. Encyclopedia links are background reading and are not used to establish clinical effectiveness.
Search for additional research
These links run searches; their results have not been individually reviewed and can include unrelated compounds.
Research information is not a dosing guide or a recommendation for personal use. Study findings are specific to the formulation, population and methods tested. Read our source and correction policy.
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