Skip to content
PeptideTech
Cart

Home / Research library / Eloralintide

Peptides

Eloralintide: molecular data, studies & sources

Eloralintide is catalogued here as a research compound. This profile brings together the molecular source record, selected indexed publications and available supplier comparisons. Evidence for a named substance does not authenticate a commercial product.

Compiled by PeptideTech Editors · Sources checked · Selected bibliography, not a systematic review

Molecular formula, weight & structure

Molecular record not yet resolved

A sufficiently specific molecular record was not resolved for this name. Formula, molecular weight and structure are withheld until the exact sequence, salt or preparation can be verified.

MF: not assigned · MW: not assigned · Structure: not assigned

Registered clinical trials

Studies registered on ClinicalTrials.gov that list Eloralintide as an intervention. Studies that only measure the molecule as a biomarker, or use it only as a comparator or background arm for another drug, are excluded. A registration describes a planned or completed protocol; it does not report a result. Active studies are listed first.

22 registered studies matched, 15 currently active or recruiting, 1 with results posted on ClinicalTrials.gov.

By highest phase
Phase 3 · 5Phase 2 · 5Phase 1 · 12
By registry status
Recruiting · 12Completed · 7Active Not Recruiting · 2Not Yet Recruiting · 1
StudyPhase · statusConditionsSponsor · size
A Study of Macupatide (LY3532226) in Participants With Obesity or Overweight Without Type 2 DiabetesNCT07765511 · start 2026-10 · primary completion 2027-06Phase 1Not Yet RecruitingObesity · OverweightEli Lilly and Company60 participants
A Study of Eloralintide (LY3841136) in Female Participants With Obesity or OverweightNCT07808060 · start 2026-09-15 · primary completion 2027-06Phase 1RecruitingObesity · OverweightEli Lilly and Company34 participants
A Study of Eloralintide (LY3841136) in Healthy ParticipantsNCT07701083 · start 2026-07-20 · primary completion 2026-10Phase 1Active Not RecruitingHealthy VolunteersEli Lilly and Company58 participants
A Study of Eloralintide (LY3841136) in Participants With Obesity or OverweightNCT07738614 · start 2026-07-31 · primary completion 2026-12Phase 1RecruitingObesity · OverweightEli Lilly and Company56 participants
A Study of Eloralintide (LY3841136) in Participants With Overweight or ObesityNCT07665879 · start 2026-06-24 · primary completion 2027-08Phase 1RecruitingOverweight · ObesityEli Lilly and Company115 participants
A Study to Investigate Weight Management With Macupatide and Eloralintide, Alone or in Combination, in Adult Participants With Obesity or OverweightNCT07589608 · start 2026-05-15 · primary completion 2027-09Phase 2RecruitingOverweight · ObesityEli Lilly and Company400 participants
A Study of Eloralintide (LY3841136) in Participants With Obesity, or Overweight Without Type 2 DiabetesNCT07321886 · start 2026-02-06 · primary completion 2028-03Phase 3RecruitingObesity · OverweightEli Lilly and Company1980 participants
Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or OverweightNCT07353931 · start 2026-02-09 · primary completion 2028-03Phase 3RecruitingOsteoarthritis · Overweight or ObesityEli Lilly and Company900 participants
A Study of Eloralintide (LY3841136) in Participants With Obstructive Sleep Apnea and Obesity or OverweightNCT07369011 · start 2026-02-10 · primary completion 2028-03Phase 3RecruitingSleep Apnea, Obstructive · Obesity · OverweightEli Lilly and Company800 participants
A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly IncretinNCT07392190 · start 2026-02-10 · primary completion 2028-06Phase 3RecruitingOverweight · ObesityEli Lilly and Company900 participants
Show 12 more registered studies
StudyPhase · statusConditionsSponsor · size
A Study of Eloralintide (LY3841136) in Participants With Different Levels of Liver Damage and in Participants With Healthy Livers.NCT07401862 · start 2026-02-10 · primary completion 2027-03Phase 1RecruitingHepatic InsufficiencyEli Lilly and Company36 participants
A Study of Eloralintide (LY3841136) in Participants With Renal Impairment and in Participants With Normal Renal FunctionNCT07426380 · start 2026-02-24 · primary completion 2026-10Phase 1Active Not RecruitingKidney Disease · Renal Insufficiency Chronic · Kidney Failure, Chronic · Renal Impairment · Renal Insufficiency · End Stage Kidney DiseaseEli Lilly and Company28 participants
A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 DiabetesNCT07282600 · start 2025-12-15 · primary completion 2028-01Phase 3RecruitingOverweight · ObesityEli Lilly and Company1035 participants
A Study of Macupatide (LY3532226) and Eloralintide (LY3841136), Alone or in Combination, in Adults With Obesity or Overweight and With Type 2 DiabetesNCT07215559 · start 2025-10-16 · primary completion 2027-03Phase 2RecruitingObesity · Overweight · Diabetes Mellitus, Type 2Eli Lilly and Company200 participants
A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or OverweightNCT06143956 · start 2023-11-17 · primary completion 2027-09Phase 2RecruitingObesity · OverweightEli Lilly and Company1481 participants
A Study of Eloralintide (LY3841136) and Eloralintide With Tirzepatide in Participants With Overweight or ObesityNCT06916065 · start 2025-04-09 · primary completion 2026-01-19Phase 1CompletedOverweight · ObesityEli Lilly and Company188 participants
A Study of Eloralintide (LY3841136) in Chinese Participants With Obesity or OverweightNCT06916091 · start 2025-04-21 · primary completion 2025-09-09Phase 1CompletedObesity · OverweightEli Lilly and Company30 participants
A Study to Investigate Weight Management With LY3841136 and Tirzepatide (LY3298176), Alone or in Combination, in Adult Participants With Obesity or Overweight With Type 2 DiabetesNCT06603571 · start 2024-09-20 · primary completion 2026-07-01Phase 2CompletedObesity · OverweightEli Lilly and Company367 participants
A Study of LY3841136 in Japanese Participants With Obesity or OverweightNCT06297616 · start 2024-04-15 · primary completion 2025-11-21Phase 1CompletedObesity · OverweightEli Lilly and Company128 participants
A Study of LY3841136 in Overweight and Obese ParticipantsNCT06345066 · start 2024-04-03 · primary completion 2025-09-29Phase 1CompletedObesity · OverweightEli Lilly and Company96 participants
A Study of LY3841136 Compared With Placebo in Adult Participants With Obesity or OverweightNCT06230523 · start 2024-02-05 · primary completion 2025-05-30Phase 2CompletedResults posted 2026-06-24Obesity · OverweightEli Lilly and Company263 participants
A Study of LY3841136 in Healthy and Overweight ParticipantsNCT05295940 · start 2022-03-30 · primary completion 2024-01-25Phase 1CompletedObesity · HealthyEli Lilly and Company148 participants

Registry check 2026-10-09 · Run this search on ClinicalTrials.gov

Human intervention studies

Selected studies in which participants received Eloralintide, with their indexed or reviewed study type. Check the original article for the formulation, population and controls. Studies that only measured the molecule, or used it as a comparator, are listed separately below and are not counted as intervention studies.

  1. Human study · PubMed trial index Compound given to participants

    Eloralintide (LY3841136), a novel amylin receptor agonist for the treatment of obesity: From discovery to clinical proof of concept.

    Briere DA, Qu H, Lansu K et al. · Molecular metabolism · 2025

    PMID 41109426 · DOI: 10.1016/j.molmet.2025.102271 · Registration NCT05295940

  2. Human study · PubMed trial index Compound given to participants

    Eloralintide, a selective amylin receptor agonist for the treatment of obesity: a 48-week phase 2, multicentre, double-blind, randomised, placebo-controlled trial.

    Billings LK, Hsia S, Bays H et al. · Lancet (London, England) · 2025

    PMID 41207310 · DOI: 10.1016/S0140-6736(25)02155-5 · Registration NCT06230523

  3. Human study · PubMed trial index Compound given to participants

    Eloralintide, a selective, long-acting amylin receptor agonist for treatment of obesity: Phase 1 proof of concept.

    Bhattachar S, Tham LS, Tidemann-Miller B et al. · Diabetes, obesity & metabolism · 2026

    PMID 41559929 · DOI: 10.1111/dom.70439

Preclinical research, reviews & other publications

Animal studies, laboratory experiments, reviews and other indexed papers answer different questions. A review is secondary evidence; a case report does not estimate how often an outcome occurs.

  1. Research publication · design requires review

    Cardiometabolic Risk Reduction Through Selective Amylin Receptor Agonism: Emerging Cardiovascular Implications of Eloralintide.

    Sigalov A, Frishman WH · Cardiology in review · 2026

    PMID 42745233 · DOI: 10.1097/CRD.0000000000001468

Eloralintide supplier sources

Scientific sources describe molecules and experiments. The commercial links below identify recorded supplier packages. A publication or chemical database entry does not verify the seller, purity, sterility or contents of a lot. Some links are affiliate links; see our disclosure.

No priced supplier offers are currently available in this catalog view. The research record remains available independently of stock.

Reference sources & further reading

    The citations above link directly to publication records. Encyclopedia links are background reading and are not used to establish clinical effectiveness.

    Search for additional research

    These links run searches; their results have not been individually reviewed and can include unrelated compounds.

    Research information is not a dosing guide or a recommendation for personal use. Study findings are specific to the formulation, population and methods tested. Read our source and correction policy.

    Related research profiles

    Peptides

    Cagrilintide

    C194H312N54O59S2

    4409 g/mol · PubChem CID 171397054

    5 selected publications · 4 human intervention studies · 40 registered trials

    Protein / peptide · highest stage: Phase 3

    Structure, studies & sources →

    Peptides

    Liraglutide

    C172H265N43O51

    3751 g/mol · PubChem CID 16134956

    7 selected publications · 4 human intervention studies · 33 registered trials

    US: active ingredient of an FDA-approved medicine · Drugs@FDA

    Protein / peptide · highest stage: Approved in at least one jurisdiction (ChEMBL phase 4)

    Structure, studies & sources →

    Peptides

    Mazdutide

    C207H317N45O65

    4476 g/mol · PubChem CID 167312357

    7 selected publications · 6 human intervention studies · 40 registered trials

    Protein / peptide · highest stage: Phase 3

    Structure, studies & sources →

    Peptides

    Semaglutide

    C187H291N45O59

    4114 g/mol · PubChem CID 56843331

    8 selected publications · 5 human intervention studies · 34 registered trials

    US: active ingredient of an FDA-approved medicine · Drugs@FDA

    Protein / peptide · highest stage: Approved in at least one jurisdiction (ChEMBL phase 4)

    Structure, studies & sources →