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Liraglutide: molecular data, studies & sources

Liraglutide is catalogued here as a research compound. This profile brings together the molecular source record, selected indexed publications and available supplier comparisons. Evidence for a named substance does not authenticate a commercial product.

Compiled by PeptideTech Editors · Sources checked · Selected bibliography, not a systematic review

Molecular formula, weight & structure

Molecular formula (MF)
C172H265N43O51
Molecular weight (MW)
3751 g/mol
PubChem compound ID
16134956
Record title
Liraglutide

Values describe the selected PubChem molecular entity. Counterions, salt forms, hydration and sequence changes can alter the supplied material. Confirm the exact identity against the supplier specification.

Source: PubChem CID 16134956 · retrieved 2026-09-21

PubChem 2D molecular structure for Liraglutide, CID 16134956
2D depiction from PubChem. Open to inspect the full image. This drawing represents the selected record, not a vendor batch test.
Chemical identifiers and source data
IUPAC name
(2S)-5-[[(5S)-5-[[(2S)-2-[[(2S)-2-[[(2S)-5-amino-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S,3R)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(1H-imidazol-5-yl)propanoyl]amino]propanoyl]amino]-4-carboxybutanoyl]amino]acetyl]amino]-3-hydroxybutanoyl]amino]-3-phenylpropanoyl]amino]-3-hydroxybutanoyl]amino]-3-hydroxypropanoyl]amino]-3-carboxypropanoyl]amino]-3-methylbutanoyl]amino]-3-hydroxypropanoyl]amino]-3-hydroxypropanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-4-methylpentanoyl]amino]-4-carboxybutanoyl]amino]acetyl]amino]-5-oxopentanoyl]amino]propanoyl]amino]propanoyl]amino]-6-[[(2S)-1-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-5-carbamimidamido-1-[[2-[[(2S)-5-carbamimidamido-1-(carboxymethylamino)-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-6-oxohexyl]amino]-2-(hexadecanoylamino)-5-oxopentanoic acid
InChIKey
YSDQQAXHVYUZIW-QCIJIYAXSA-N
SMILES
CCCCCCCCCCCCCCCC(=O)N[C@@H](CCC(=O)NCCCC[C@@H](C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CC2=CNC3=CC=CC=C32)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(=O)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC4=CC=C(C=C4)O)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC5=CC=CC=C5)NC(=O)[C@H]([C@@H](C)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C)NC(=O)[C@H](CC6=CN=CN6)N)C(=O)O
Machine-readable PubChem source

Human and clinical studies

Selected human-study records are shown with their indexed or reviewed study type. Check the original article for the intervention, formulation and controls; the molecule can also be a comparator or measured variable.

  1. Human study · PubMed trial index

    Effect of Weekly Subcutaneous Semaglutide vs Daily Liraglutide on Body Weight in Adults With Overweight or Obesity Without Diabetes: The STEP 8 Randomized Clinical Trial.

    Rubino DM, Greenway FL, Khalid U et al. · JAMA · 2022

    PMID 35015037 · DOI: 10.1001/jama.2021.23619

  2. Human study · PubMed trial index

    Liraglutide for Children 6 to <12 Years of Age with Obesity - A Randomized Trial.

    Fox CK, Barrientos-Pérez M, Bomberg EM et al. · The New England journal of medicine · 2025

    PMID 39258838 · DOI: 10.1056/NEJMoa2407379

  3. Human study · PubMed trial index

    A Randomized, Controlled Trial of 3.0 mg of Liraglutide in Weight Management.

    Pi-Sunyer X, Astrup A, Fujioka K et al. · The New England journal of medicine · 2015

    PMID 26132939 · DOI: 10.1056/NEJMoa1411892

  4. Human study · PubMed trial index

    Healthy Weight Loss Maintenance with Exercise, Liraglutide, or Both Combined.

    Lundgren JR, Janus C, Jensen SBK et al. · The New England journal of medicine · 2021

    PMID 33951361 · DOI: 10.1056/NEJMoa2028198

  5. Human study · PubMed trial index

    Liraglutide and Cardiovascular Outcomes in Type 2 Diabetes.

    Marso SP, Daniels GH, Brown-Frandsen K et al. · The New England journal of medicine · 2016

    PMID 27295427 · DOI: 10.1056/NEJMoa1603827

Preclinical research, reviews & other publications

Animal studies, laboratory experiments, reviews and other indexed papers answer different questions. A review is secondary evidence; a case report does not estimate how often an outcome occurs.

  1. Preclinical / laboratory research

    The arcuate nucleus mediates GLP-1 receptor agonist liraglutide-dependent weight loss.

    Secher A, Jelsing J, Baquero AF et al. · The Journal of clinical investigation · 2014

    PMID 25202980 · DOI: 10.1172/JCI75276

  2. Preclinical / laboratory research

    Liraglutide attenuates type 2 diabetes mellitus-associated non-alcoholic fatty liver disease by activating AMPK/ACC signaling and inhibiting ferroptosis.

    Guo T, Yan W, Cui X et al. · Molecular medicine (Cambridge, Mass.) · 2023

    PMID 37770820 · DOI: 10.1186/s10020-023-00721-7

Liraglutide supplier sources

Scientific sources describe molecules and experiments. The commercial links below identify recorded supplier packages. A publication or chemical database entry does not verify the seller, purity, sterility or contents of a lot. Some links are affiliate links; see our disclosure.

Compare all Liraglutide sizes, forms and supplier prices →

SupplierRecorded packagesExample source listing
Amino USAUSD5mg Vial1 recorded offers5mg Vial · $45.90Checked Sep 16, 2026Supplier listing

Reference sources & further reading

The citations above link directly to publication records. Encyclopedia links are background reading and are not used to establish clinical effectiveness.

Search for additional research

These links run searches; their results have not been individually reviewed and can include unrelated compounds.

Research information is not a dosing guide or a recommendation for personal use. Study findings are specific to the formulation, population and methods tested. Read our source and correction policy.

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