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NAD+: molecular data, studies & sources

A small human pilot study measured plasma and urine metabolites during an intravenous NAD infusion. It examined metabolite handling, not proof of an anti-aging benefit. Trials of NMN, nicotinamide riboside or other precursors are not interchangeable with studies of NAD itself.

Overview sources: PMID 31572171

Compiled by PeptideTech Editors · Sources checked · Selected bibliography, not a systematic review

Molecular formula, weight & structure

Molecular formula (MF)
C21H27N7O14P2
Molecular weight (MW)
663.4 g/mol
PubChem compound ID
5892
Record title
Nadide

The selected structure is oxidized nicotinamide adenine dinucleotide. NADH and NAD precursors such as NMN or nicotinamide riboside are different chemical identities; their trials are not evidence for direct NAD administration.

Source: PubChem CID 5892 · retrieved 2026-09-21

PubChem 2D molecular structure for NAD+, CID 5892
2D depiction from PubChem. Open to inspect the full image. This drawing represents the selected record, not a vendor batch test.
Chemical identifiers and source data
IUPAC name
[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphate
InChIKey
BAWFJGJZGIEFAR-NNYOXOHSSA-N
SMILES
C1=CC(=C[N+](=C1)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)([O-])OP(=O)(O)OC[C@@H]3[C@H]([C@H]([C@@H](O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N
Machine-readable PubChem source

Human and clinical studies

Selected human-study records are shown with their indexed or reviewed study type. Check the original article for the intervention, formulation and controls; the molecule can also be a comparator or measured variable.

  1. Human pilot study

    A Pilot Study Investigating Changes in the Human Plasma and Urine NAD+ Metabolome During a 6 Hour Intravenous Infusion of NAD.

    Grant R, Berg J, Mestayer R et al. · Frontiers in aging neuroscience · 2019

    Small human pilot measuring NAD-related metabolites during infusion. It does not demonstrate clinical anti-aging efficacy.

    PMID 31572171 · DOI: 10.3389/fnagi.2019.00257

Preclinical research, reviews & other publications

Animal studies, laboratory experiments, reviews and other indexed papers answer different questions. A review is secondary evidence; a case report does not estimate how often an outcome occurs.

No additional matching publication was retained. The search links below allow further investigation; they are not evidence that a study exists.

    NAD+ supplier sources

    Scientific sources describe molecules and experiments. The commercial links below identify recorded supplier packages. A publication or chemical database entry does not verify the seller, purity, sterility or contents of a lot. Some links are affiliate links; see our disclosure.

    Compare all NAD+ sizes, forms and supplier prices →

    SupplierRecorded packagesExample source listing
    Blank PeptidesUSD500mg Vial · 1000mg Vial2 recorded offers500mg Vial · $60.00Checked Sep 21, 2026Supplier listing
    American PeptidesUSD500mg Spray · 1000mg Vial2 recorded offers500mg Spray · $100.00Checked Sep 21, 2026Supplier listing
    Modified AminosUSD500mg Vial · 1500mg Spray · 500mg Spray3 recorded offers500mg Vial · $44.99Checked Sep 16, 2026Supplier listing
    Amino ClubUSD500mg Vial · 750mg Spray2 recorded offers500mg Vial · $69.99Checked Sep 16, 2026Supplier listing
    Nova Peptide SupplyUSD500mg Vial · 1000mg Spray · 1500mg Spray3 recorded offers500mg Vial · $79.99Checked Sep 16, 2026Supplier listing
    Amino USAUSD1000mg Vial · 500mg Vial2 recorded offers1000mg Vial · $207.00Checked Sep 16, 2026Supplier listing
    Cenexa LabsUSD500mg Vial1 recorded offers500mg Vial · $99.99Checked Sep 16, 2026Supplier listing
    US Peptide LabsUSD500mg Vial · 500mg Oral spray · 500mg Spray3 recorded offers500mg Vial · $80.00Checked Sep 16, 2026Supplier listing
    Direct PeptidesUSD500mg Vial · 1000mg Vial2 recorded offers500mg Vial · $79.00Checked Sep 16, 2026Supplier listing
    PeptiLabCAD500mg Vial1 recorded offers500mg Vial · CA$59.00Checked Sep 17, 2026Supplier listing
    Nuvion PeptidesCAD500mg Vial1 recorded offers500mg Vial · CA$64.99Checked Sep 21, 2026Supplier listing
    PhaseOneAUD1000mg Vial1 recorded offers1000mg Vial · A$71.99Checked Sep 21, 2026Supplier listing
    BioStacksCAD500mg Vial · 1000mg Vial2 recorded offers500mg Vial · CA$130.00Recorded out of stock · Checked Sep 21, 2026Supplier listing
    PepspanEUR500mg Vial1 recorded offers500mg Vial · €64.90Checked Sep 21, 2026Supplier listing

    Reference sources & further reading

    The citations above link directly to publication records. Encyclopedia links are background reading and are not used to establish clinical effectiveness.

    Search for additional research

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