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Thymosin Alpha-1: molecular data, studies & sources

Thymosin Alpha-1 is catalogued here as a research compound. This profile brings together the molecular source record, selected indexed publications and available supplier comparisons. Evidence for a named substance does not authenticate a commercial product.

Compiled by PeptideTech Editors · Sources checked · Selected bibliography, not a systematic review

Molecular formula, weight & structure

Molecular formula (MF)
C129H215N33O55
Molecular weight (MW)
3108.3 g/mol
PubChem compound ID
16130571
Record title
Thymalfasin

Values describe the selected PubChem molecular entity. Counterions, salt forms, hydration and sequence changes can alter the supplied material. Confirm the exact identity against the supplier specification.

Source: PubChem CID 16130571 · retrieved 2026-09-21

PubChem 2D molecular structure for Thymosin Alpha-1, CID 16130571
2D depiction from PubChem. Open to inspect the full image. This drawing represents the selected record, not a vendor batch test.
Chemical identifiers and source data
IUPAC name
(4S)-4-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S,3R)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-3-hydroxypropanoyl]amino]-3-carboxypropanoyl]amino]propanoyl]amino]propanoyl]amino]-3-methylbutanoyl]amino]-3-carboxypropanoyl]amino]-3-hydroxybutanoyl]amino]-3-hydroxypropanoyl]amino]-3-hydroxypropanoyl]amino]-4-carboxybutanoyl]amino]-3-methylpentanoyl]amino]-3-hydroxybutanoyl]amino]-3-hydroxybutanoyl]amino]-6-aminohexanoyl]amino]-3-carboxypropanoyl]amino]-4-methylpentanoyl]amino]-6-aminohexanoyl]amino]-4-carboxybutanoyl]amino]-6-aminohexanoyl]amino]-6-aminohexanoyl]amino]-4-carboxybutanoyl]amino]-3-methylbutanoyl]amino]-3-methylbutanoyl]amino]-4-carboxybutanoyl]amino]-4-carboxybutanoyl]amino]propanoyl]amino]-5-[[(1S)-3-amino-1-carboxy-3-oxopropyl]amino]-5-oxopentanoic acid
InChIKey
NZVYCXVTEHPMHE-ZSUJOUNUSA-N
SMILES
CC[C@H](C)[C@@H](C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(=O)N)C(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)C
Machine-readable PubChem source

Human and clinical studies

Selected human-study records are shown with their indexed or reviewed study type. Check the original article for the intervention, formulation and controls; the molecule can also be a comparator or measured variable.

  1. Human study · PubMed trial index

    Thymosin alpha 1 is associated with improved cellular immunity and reduced infection rate in severe acute pancreatitis patients in a double-blind randomized control study.

    Wang X, Li W, Niu C et al. · Inflammation · 2011

    PMID 20549321 · DOI: 10.1007/s10753-010-9224-1

  2. Human study · PubMed trial index

    A randomized, controlled, clinical study of thymosin alpha-1 versus interferon-alpha in [corrected] patients with chronic hepatitis B lacking HBeAg in China [corrected].

    You J, Zhuang L, Cheng HY et al. · Journal of the Chinese Medical Association : JCMA · 2005

    PMID 15759817 · DOI: 10.1016/s1726-4901(09)70137-6

  3. Human study · PubMed trial index

    Polyethylene glycol-modified interleukin-2 and thymosin alpha 1 in human immunodeficiency virus type 1 infection.

    Ramachandran R, Katzenstein DA, Winters MA et al. · The Journal of infectious diseases · 1996

    PMID 8603940 · DOI: 10.1093/infdis/173.4.1005

Preclinical research, reviews & other publications

Animal studies, laboratory experiments, reviews and other indexed papers answer different questions. A review is secondary evidence; a case report does not estimate how often an outcome occurs.

  1. Review · secondary evidence

    Thymosin alpha-1.

    Ancell CD, Phipps J, Young L et al. · American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists · 2001

    PMID 11381492 · DOI: 10.1093/ajhp/58.10.886

  2. Review · secondary evidence

    Aging and Thymosin Alpha-1.

    Simonova MA, Ivanov I, Shoshina NS et al. · International journal of molecular sciences · 2025

    PMID 41373628 · DOI: 10.3390/ijms262311470

  3. Research publication · design requires review

    Thymosin alpha-1 treatment in chronic hepatitis B.

    Wu X, Jia J, You H et al. · Expert opinion on biological therapy · 2015

    PMID 25640173 · DOI: 10.1517/14712598.2015.1007948

Thymosin Alpha-1 supplier sources

Scientific sources describe molecules and experiments. The commercial links below identify recorded supplier packages. A publication or chemical database entry does not verify the seller, purity, sterility or contents of a lot. Some links are affiliate links; see our disclosure.

Compare all Thymosin Alpha-1 sizes, forms and supplier prices →

SupplierRecorded packagesExample source listing
Blank PeptidesUSD10mg Vial1 recorded offers10mg Vial · $75.00Checked Sep 21, 2026Supplier listing
American PeptidesUSD10mg Vial1 recorded offers10mg Vial · $125.00Checked Sep 21, 2026Supplier listing
Amino ClubUSD10mg Vial1 recorded offers10mg Vial · $39.99Checked Sep 16, 2026Supplier listing
Amino USAUSD5mg Vial1 recorded offers5mg Vial · $54.00Checked Sep 16, 2026Supplier listing
Cenexa LabsUSD10mg Vial1 recorded offers10mg Vial · $129.99Checked Sep 16, 2026Supplier listing
US Peptide LabsUSD10mg Vial1 recorded offers10mg Vial · $118.00Checked Sep 16, 2026Supplier listing
Direct PeptidesUSD10mg Vial1 recorded offers10mg Vial · $99.00Checked Sep 16, 2026Supplier listing
Particle PeptidesEUR5mg Vial1 recorded offers5mg Vial · €49.99Checked Sep 16, 2026Supplier listing
Nuvion PeptidesCAD10mg Vial1 recorded offers10mg Vial · CA$119.99Checked Sep 21, 2026Supplier listing
AminoVaultUSD10mg Vial1 recorded offers10mg Vial · $89.25Checked Sep 19, 2026Supplier listing
BioStacksCAD10mg Vial1 recorded offers10mg Vial · CA$120.00Checked Sep 21, 2026Supplier listing

Reference sources & further reading

The citations above link directly to publication records. Encyclopedia links are background reading and are not used to establish clinical effectiveness.

Search for additional research

These links run searches; their results have not been individually reviewed and can include unrelated compounds.

Research information is not a dosing guide or a recommendation for personal use. Study findings are specific to the formulation, population and methods tested. Read our source and correction policy.

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