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Tirzepatide: molecular data, studies & sources

Tirzepatide is catalogued here as a research compound. This profile brings together the molecular source record, selected indexed publications and available supplier comparisons. Evidence for a named substance does not authenticate a commercial product.

Compiled by PeptideTech Editors · Sources checked · Selected bibliography, not a systematic review

Molecular formula, weight & structure

Molecular formula (MF)
C225H348N48O68
Molecular weight (MW)
4813 g/mol
PubChem compound ID
156588324
Record title
Tirzepatide

Values describe the selected PubChem molecular entity. Counterions, salt forms, hydration and sequence changes can alter the supplied material. Confirm the exact identity against the supplier specification.

Source: PubChem CID 156588324 · retrieved 2026-09-21

PubChem 2D molecular structure for Tirzepatide, CID 156588324
2D depiction from PubChem. Open to inspect the full image. This drawing represents the selected record, not a vendor batch test.
Chemical identifiers and source data
IUPAC name
(2S)-2-[[20-[[(5S)-6-[[(2S,3S)-1-[[(2S)-1-[[(2S)-5-amino-1-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1-[[2-[[2-[(2S)-2-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[(2S)-2-[(2S)-2-[(2S)-2-[[(2S)-1-amino-3-hydroxy-1-oxopropan-2-yl]carbamoyl]pyrrolidine-1-carbonyl]pyrrolidine-1-carbonyl]pyrrolidin-1-yl]-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]carbamoyl]pyrrolidin-1-yl]-2-oxoethyl]amino]-2-oxoethyl]amino]-1-oxopropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-5-[[(2S)-2-[[(2S)-2-[[2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S,3R)-2-[[2-[[(2S)-2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-2-methylpropanoyl]amino]-4-carboxybutanoyl]amino]acetyl]amino]-3-hydroxybutanoyl]amino]-3-phenylpropanoyl]amino]-3-hydroxybutanoyl]amino]-3-hydroxypropanoyl]amino]-3-carboxypropanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-hydroxypropanoyl]amino]-3-methylpentanoyl]amino]-2-methylpropanoyl]amino]-4-methylpentanoyl]amino]-3-carboxypropanoyl]amino]-6-oxohexyl]amino]-20-oxoicosanoyl]amino]-5-[2-[2-[2-[2-[2-(carboxymethoxy)ethoxy]ethylamino]-2-oxoethoxy]ethoxy]ethylamino]-5-oxopentanoic acid
InChIKey
AAPYRSPHYSKGIS-MCNPHUAVSA-N
SMILES
CC[C@H](C)[C@@H](C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC2=CNC3=CC=CC=C32)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)NCC(=O)NCC(=O)N4CCC[C@H]4C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](C)C(=O)N5CCC[C@H]5C(=O)N6CCC[C@H]6C(=O)N7CCC[C@H]7C(=O)N[C@@H](CO)C(=O)N)NC(=O)[C@H](CCCCNC(=O)CCCCCCCCCCCCCCCCCCC(=O)N[C@@H](CCC(=O)NCCOCCOCC(=O)NCCOCCOCC(=O)O)C(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)C(C)(C)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](CO)NC(=O)[C@H](CC8=CC=C(C=C8)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC9=CC=CC=C9)NC(=O)[C@H]([C@@H](C)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)C(C)(C)NC(=O)[C@H](CC1=CC=C(C=C1)O)N
Machine-readable PubChem source

Human and clinical studies

Selected human-study records are shown with their indexed or reviewed study type. Check the original article for the intervention, formulation and controls; the molecule can also be a comparator or measured variable.

  1. Human study · PubMed trial index

    Tirzepatide for the Treatment of Obstructive Sleep Apnea and Obesity.

    Malhotra A, Grunstein RR, Fietze I et al. · The New England journal of medicine · 2024

    PMID 38912654 · DOI: 10.1056/NEJMoa2404881

  2. Human study · PubMed trial index

    Tirzepatide Once Weekly for the Treatment of Obesity.

    Jastreboff AM, Aronne LJ, Ahmad NN et al. · The New England journal of medicine · 2022

    PMID 35658024 · DOI: 10.1056/NEJMoa2206038

  3. Human study · PubMed trial index

    Tirzepatide for Obesity Treatment and Diabetes Prevention.

    Jastreboff AM, le Roux CW, Stefanski A et al. · The New England journal of medicine · 2025

    PMID 39536238 · DOI: 10.1056/NEJMoa2410819

  4. Human study · PubMed trial index

    Continued Treatment With Tirzepatide for Maintenance of Weight Reduction in Adults With Obesity: The SURMOUNT-4 Randomized Clinical Trial.

    Aronne LJ, Sattar N, Horn DB et al. · JAMA · 2024

    PMID 38078870 · DOI: 10.1001/jama.2023.24945

  5. Human study · PubMed trial index

    Tirzepatide for Heart Failure with Preserved Ejection Fraction and Obesity.

    Packer M, Zile MR, Kramer CM et al. · The New England journal of medicine · 2025

    PMID 39555826 · DOI: 10.1056/NEJMoa2410027

  6. Human study · PubMed trial index

    Tirzepatide versus Semaglutide Once Weekly in Patients with Type 2 Diabetes.

    Frías JP, Davies MJ, Rosenstock J et al. · The New England journal of medicine · 2021

    PMID 34170647 · DOI: 10.1056/NEJMoa2107519

  7. Human study · PubMed trial index

    Tirzepatide for Metabolic Dysfunction-Associated Steatohepatitis with Liver Fibrosis.

    Loomba R, Hartman ML, Lawitz EJ et al. · The New England journal of medicine · 2024

    PMID 38856224 · DOI: 10.1056/NEJMoa2401943

Preclinical research, reviews & other publications

Animal studies, laboratory experiments, reviews and other indexed papers answer different questions. A review is secondary evidence; a case report does not estimate how often an outcome occurs.

  1. Review · secondary evidence

    Tirzepatide: A Review in Type 2 Diabetes.

    France NL, Syed YY · Drugs · 2024

    PMID 38388874 · DOI: 10.1007/s40265-023-01992-4

Tirzepatide supplier sources

Scientific sources describe molecules and experiments. The commercial links below identify recorded supplier packages. A publication or chemical database entry does not verify the seller, purity, sterility or contents of a lot. Some links are affiliate links; see our disclosure.

Compare all Tirzepatide sizes, forms and supplier prices →

SupplierRecorded packagesExample source listing
Blank PeptidesUSD10mg Vial · 30mg Vial2 recorded offers10mg Vial · $89.00Checked Sep 21, 2026Supplier listing
Modified AminosUSD30mg Vial · 10mg Vial · 60mg Vial3 recorded offers30mg Vial · $119.99Checked Sep 16, 2026Supplier listing
American PeptidesUSD10mg Vial · 30mg Vial · 60mg Vial · 20mg Vial4 recorded offers10mg Vial · $100.00Checked Sep 21, 2026Supplier listing
Amino ClubUSD30mg Vial · 60mg Vial2 recorded offers30mg Vial · $59.99Checked Sep 16, 2026Supplier listing
US Peptide LabsUSD10mg Vial · 40mg Vial · 40mg Nasal spray · 20mg Oral spray4 recorded offers10mg Vial · $76.00Checked Sep 16, 2026Supplier listing
Direct PeptidesUSD10mg Vial · 15mg Vial · 30mg Vial3 recorded offers10mg Vial · $69.00Checked Sep 16, 2026Supplier listing
Nuvion PeptidesCAD30mg Vial · 10mg Vial2 recorded offers30mg Vial · CA$119.99Checked Sep 21, 2026Supplier listing
PhaseOneAUD10mg Vial1 recorded offers10mg Vial · A$109.99Checked Sep 21, 2026Supplier listing

Reference sources & further reading

The citations above link directly to publication records. Encyclopedia links are background reading and are not used to establish clinical effectiveness.

Search for additional research

These links run searches; their results have not been individually reviewed and can include unrelated compounds.

Research information is not a dosing guide or a recommendation for personal use. Study findings are specific to the formulation, population and methods tested. Read our source and correction policy.

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