S-23: molecular data, studies & sources

Molecular formula, weight & structure

Molecular formula (MF)

C18H13ClF4N2O3

Molecular weight (MW)

416.8 g/mol

PubChem compound ID

24892822

Record title

(2S)-3-(4-chloro-3-fluorophenoxy)-N-(4-cyano-3-(trifluoromethyl)phenyl)-2-hydroxy-2-methylpropanamide

Values describe the selected PubChem molecular entity. Counterions, salt forms, hydration and sequence changes can alter the supplied material. Confirm the exact identity against the supplier specification.

Source: PubChem CID 24892822 · retrieved 2026-10-09

Registered clinical trials

Studies registered on ClinicalTrials.gov that list S-23 as an intervention. Studies that only measure the molecule as a biomarker, or use it only as a comparator or background arm for another drug, are excluded. A registration describes a planned or completed protocol; it does not report a result. Active studies are listed first.

No registered study naming this compound was matched. This is a documented gap in registry coverage, not proof that no study exists.

Registry check 2026-10-01 · Run this search on ClinicalTrials.gov

Human intervention studies

Selected studies in which participants received S-23, with their indexed or reviewed study type. Check the original article for the formulation, population and controls. Studies that only measured the molecule, or used it as a comparator, are listed separately below and are not counted as intervention studies.

No human study that administered this compound was retained in this selected bibliography. This is a documented evidence gap in our selection, not proof that no study exists.

Preclinical research, reviews & other publications

Animal studies, laboratory experiments, reviews and other indexed papers answer different questions. A review is secondary evidence; a case report does not estimate how often an outcome occurs.

1. Preclinical / laboratory research

   Preclinical characterization of a (S)-N-(4-cyano-3-trifluoromethyl-phenyl)-3-(3-fluoro, 4-chlorophenoxy)-2-hydroxy-2-methyl-propanamide: a selective androgen receptor modulator for hormonal male contraception.

   Jones A, Chen J, Hwang DJ et al. · Endocrinology · 2009

   PMID 18772237 · DOI: 10.1210/en.2008-0674

2. Preclinical / laboratory research

   Nonsteroidal selective androgen receptor modulators enhance female sexual motivation.

   Jones A, Hwang DJ, Duke CB et al. · The Journal of pharmacology and experimental therapeutics · 2010

   PMID 20444881 · DOI: 10.1124/jpet.110.168880

3. Preclinical / laboratory research

   Metabolic studies of selective androgen receptor modulators RAD140 and S-23 in horses.

   So YM, Wong JKY, Choi TLS et al. · Drug testing and analysis · 2021

   PMID 32853476 · DOI: 10.1002/dta.2920

S-23 supplier sources

Scientific sources describe molecules and experiments. The commercial links below identify recorded supplier packages. A publication or chemical database entry does not verify the seller, purity, sterility or contents of a lot. Some links are affiliate links; see our disclosure.

No priced supplier offers are currently available in this catalog view. The research record remains available independently of stock.

Reference sources & further reading

• PubChem compound record 24892822 — chemical identity and structure.
• FDA Global Substance Registration System: UNII XDK89456WM — substance identity, names and codes.

The citations above link directly to publication records. Encyclopedia links are background reading and are not used to establish clinical effectiveness.

Research information is not a dosing guide or a recommendation for personal use. Study findings are specific to the formulation, population and methods tested. Read our source and correction policy.

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